Evidence map›Paper›PMID 28724055›Full record

ArticleArchives of endocrinology and metabolism

Bone turnover after bariatric surgery.

Thalita Lima Melo, Leila Froeder, Leandro da Cunha Baia, Ita Pfeferman Heilberg

Abstract read
In one paragraph

Article in Archives of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thalita Lima MeloDisciplina de Nefrologia, Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil.
Leila FroederDisciplina de Nefrologia, Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil.
Leandro da Cunha BaiaDisciplina de Nefrologia, Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil.
Ita Pfeferman HeilbergDisciplina de Nefrologia, Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of the present study was to evaluate parameters of bone and mineral metabolism after bariatric surgery. SUBJECTS AND

methodsThis sectional study included data from medical records from 61 bariatric surgery (BS) patients (minimum period of 6 months after the procedure) and from 30 class II and III obese patients as a control group (Cont), consisting of daily dietary intake of macronutrients, calcium and sodium, serum 25(OH)D and parathyroid hormone (PTH) and other biochemical serum and urinary parameters. Bone alkaline phosphatase (BAP), leptin, fibroblast growth factor-23 (FGF-23) and deoxypyridinoline (DPYD) were determined from available banked serum and urinary samples.

resultsMean body mass index (BMI), median energy, carbohydrate, protein and sodium chloride consumption were significantly lower in the BS versus Cont, but calcium and lipids were not. No significant differences were found in ionized calcium, 25(OH)D, PTH and fibroblast growth factor 23 (FGF-23) between groups. Mean serum BAP was significantly higher for BS versus Cont and had a positive correlation with time after the surgical procedure. Mean serum leptin was significantly lower and median urinary DPYD higher in BS versus Cont.

conclusionThe present study showed an increase in bone markers of both bone formation and resorption among bariatric patients up to more than 7 years after the surgical procedure, suggesting that an increased bone turnover persists even at a very long-term follow-up in such patients.

Indexed as

AdultAlkaline PhosphataseAmino AcidsBiliopancreatic DiversionBone and BonesBone RemodelingCalciumFemaleFibroblast Growth Factor-23Gastric BypassHumansMaleMiddle AgedObesityPostoperative PeriodRetrospective StudiesAlkaline PhosphataseAmino AcidsCalciumdeoxypyridinolineFGF23 protein, humanFibroblast Growth Factor-23Sodium

Identifiers

PMID28724055
PMCPMC10118938

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.