ArticlePediatric research2017
Association between supraclavicular brown adipose tissue composition at birth and adiposity gain from birth to 6 months of age.
Article in Pediatric research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed.
- Early postnatal antibiotic-associated gut microbiota alterations might promote long-term lipid metabolism via brown adipose tissue metabolic programming.Gut microbes · 2026Article
- Maternal nitrate supplementation improves offspring cardiometabolic outcomes in obese pregnancies.Annals of medicine · 2025Article
- Dynamics of the Epigenome, Microbiome, and Metabolome in Relation to Early Adiposity in the Maternal-Infant Axis: Protocol for a Prospective, Observational Pilot Study in the Spanish NEMO Cohort.Journal of clinical medicine · 2025Article
- The Notch-PDGFRβ axis suppresses brown adipocyte progenitor differentiation in early post-natal mice.Developmental cell · 2024Article
- Impact of brown adipose tissue vascular density on body adiposity in healthy Japanese infants and children.Obesity science & practice · 2022Article
- Practical application of in vivo MRI-based brown adipose tissue measurements in infants.Obesity (Silver Spring, Md.) · 2021Article
- Brown Adipose Tissue: New Challenges for Prevention of Childhood Obesity. A Narrative Review.Nutrients · 2021Review
- Lycopene supplementation of maternal and weanling high-fat diets influences adipose tissue development and metabolic outcomes of Sprague-Dawley offspring.Journal of nutritional science · 2021Article
- Both proliferation and lipogenesis of brown adipocytes contribute to postnatal brown adipose tissue growth in mice.Scientific reports · 2020Article
- Frataxin deficiency induces lipid accumulation and affects thermogenesis in brown adipose tissue.Cell death & disease · 2020Article
- Free-breathing 3-D quantification of infant body composition and hepatic fat using a stack-of-radial magnetic resonance imaging technique.Pediatric radiology · 2019Article
- Brown and Brite: The Fat Soldiers in the Anti-obesity Fight.Frontiers in physiology · 2019Review
- Mechanisms of Impaired Brown Adipose Tissue Recruitment in Obesity.Frontiers in physiology · 2019Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
BackgroundBrown adipose tissue (BAT) is associated with higher energy expenditure and lower adiposity in adults. However, the relationship between BAT composition and adiposity in early life is unknown. The objective of this study was to test the hypothesis that brown fat composition at birth is prospectively associated with adiposity gain during the first 6 months of postnatal life.MethodsN=35 healthy infants were followed up prospectively from intrauterine life and birth through 6 months of age. Dixon magnetic resonance imaging (MRI) scans were conducted during the neonatal period to characterize supraclavicular BAT composition. Dual-energy X-ray absorptiometry to assess total body composition was performed within the first and sixth months of life.ResultsAfter adjusting for potential confounding factors, a more brown-like composition (smaller fat fraction) of the supraclavicular BAT depot was associated with a smaller increase in percent body fat over the first 6 months of postnatal life.ConclusionsA more brown-like BAT composition at birth appears to be protective against excess adiposity gain in early life. Newborn BAT tissue may constitute a target for prevention strategies against the subsequent development of obesity.
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