ArticleMedicine2017
Initial application of transanal endoscopic microsurgery for high-risk lower rectal gastrointestinal stromal tumor after imatinib mesylate neoadjuvant chemotherapy: A case report.
Article in Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 20 citations in OpenAlex.
- Transvaginal removal of rectal stromal tumor with Martius flap interposition: a feasible option for a large tumor at the anterior wall of the rectum.Annals of coloproctology · 2024Article
- Rare rectal gastrointestinal stromal tumor case: A case report and review of the literature.World journal of clinical cases · 2023Article
- Transanal endoscopic microsurgery: exploring its indications and novel applications. A narrative review.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2022Review
- Recent Advancements in the Treatment of Rectal Gastrointestinal Stromal Tumor: In Era of Imatinib.Cancer management and research · 2022Review
- Successful Endoscopic Resection of a Rectal Gastrointestinal Stromal Tumor Larger Than 5 cm.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2021Article
- Transvaginal Resection of a Rectal Gastrointestinal Stromal Tumor: A Case Report.Journal of medical cases · 2021Article
- Transvaginal excision of rectal stromal tumors: case reports and a literature review.World journal of surgical oncology · 2019Review
- A Population-Based Study of the Incidence and Survival of Anorectal Gastrointestinal Stromal Tumor.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Management of a case of high-risk gastrointestinal stromal tumor in rectum by transanal minimal invasive surgery.World journal of surgical oncology · 2018Article
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4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
rationaleThe lower rectal gastrointestinal stromal tumor (GIST) is a rare entity and warrants special attentions because of the considerations of preserving of anal and urinal functions. Neoadjuvant therapy with imatinib mesylate (IM) has achieved great success in GIST, which potentially extends the applications of function-preserving minimally invasive surgical procedures. Transanal endoscopic microsurgery (TEM) is a well-developed minimally invasive technique for benign tumors in lower rectum. Herein, we reported the initial application of TEM for high risk GIST after IM treatment. PATIENT CONCERNS: A 52-year-old woman suffered mild lower abdominal pain and perianal discomfort. Physical examination found a soft mass 4 cm far away from anal verge. Rectal MRI and transrectal ultrasound (TRUS) showed that there was a 1.9 × 1.6 cm submucosal mass in the lower rectum. The incisional biopsy was performed and the pathological result reported it was a high-risk GIST. DIAGNOSES: High-risk lower rectal GIST.
interventionsIM was given for neoadjuvant therapy. Then TEM was adopted to resect the residual tumor. IM was restored 4 weeks after surgery. OUTCOMES: The final pathological results reported the margin was clear. After an 18-month follow up, no recurrence and metastasis was found and the patient had a satisfactory anal and urinal functions. LESSONS: TEM in combination with IM could be a practical strategy for the high-risk lower rectal GIST simultaneously to achieve curative resection and to preserve the anal and urinal functions that can significantly improve the life quality of the patients.
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