Evidence map›Paper›PMID 28723241›Full record

ArticleChannels (Austin, Tex.)2017

The effects of stretch activation on ionic selectivity of the TREK-2 K2P K

Ehsan Nematian-Ardestani, Viwan Jarerattanachat, Prafulla Aryal, Mark S P Sansom, Stephen J Tucker

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Channels (Austin, Tex.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Conductance selectivity of NaProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  3. Article
  4. Asymmetric mechanosensitivity in a eukaryotic ion channel.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ehsan Nematian-Ardestania Clarendon Laboratory, Department of Physics and OXION Initiative in Ion Channels and Disease , University of Oxford , Oxford , UK.
Viwan Jarerattanachata Clarendon Laboratory, Department of Physics and OXION Initiative in Ion Channels and Disease , University of Oxford , Oxford , UK.
Prafulla Aryala Clarendon Laboratory, Department of Physics and OXION Initiative in Ion Channels and Disease , University of Oxford , Oxford , UK.
Mark S P Sansoma Clarendon Laboratory, Department of Physics and OXION Initiative in Ion Channels and Disease , University of Oxford , Oxford , UK.ORCID http://orcid.org/0000-0001-6360-7959
Stephen J Tuckera Clarendon Laboratory, Department of Physics and OXION Initiative in Ion Channels and Disease , University of Oxford , Oxford , UK.ORCID http://orcid.org/0000-0001-8996-2000
University of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The TREK-2 (KCNK10) K2P potassium channel can be regulated by variety of polymodal stimuli including pressure. In a recent study, we demonstrated that this mechanosensitive K

Indexed as

Binding SitesCell LineHumansIon Channel GatingIonsMolecular Dynamics SimulationPotassium Channels, Tandem Pore DomainProtein BindingStress, MechanicalIonsKCNK10 protein, humanPotassium Channels, Tandem Pore DomainIon selectivityK2P channelK+ channelKCNK10MechanosensitiveTREK-2

Identifiers

PMID28723241
PMCPMC5626358
OpenAlexW2738108653

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.