Evidence map›Paper›PMID 28723237›Full record

ArticleChannels (Austin, Tex.)2017

Linking chanelopathies with endoplasmic reticulum associated degradation.

Brighid M O'Donnell, Timothy D Mackie, Jeffrey L Brodsky

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Channels (Austin, Tex.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Brighid M O'Donnella Department of Biological Sciences , University of Pittsburgh , Pittsburgh , PA , USA.
Timothy D Mackiea Department of Biological Sciences , University of Pittsburgh , Pittsburgh , PA , USA.
Jeffrey L Brodskya Department of Biological Sciences , University of Pittsburgh , Pittsburgh , PA , USA.

Funding

Single Nephron and MetabolomicsP30DK079307 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CARATTINO, MARCELO DANIEL · 2008 to 2022
$13.4M
Molecular Basis of Pediatric DiseaseK12HD052892 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TERENCE S. DERMODY · 2007 to 2026
$6.5M
ER Associated Degradation of Membrane Proteins in YeastR01GM075061 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BRODSKY, JEFFREY L. · 2006 to 2019
$3.2M
Institutional Research Training in Pediatric GastroenterologyT32DK071492 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HUSAIN, SOHAIL Z · 2006 to 2015
$1.1M
NICHD NIH HHS K12 HD052892NIDDK NIH HHS P30 DK079307NIDDK NIH HHS T32 DK071492NIGMS NIH HHS R01 GM075061
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Endoplasmic Reticulum-Associated DegradationAmino Acid SubstitutionBartter SyndromeCell MembraneHEK293 CellsHumansMutant ProteinsMutationPotassium Channels, Inwardly RectifyingProtein Aggregation, PathologicalProtein Conformation, beta-StrandProtein StabilitySaccharomyces cerevisiaeStructure-Activity RelationshipMutant ProteinsPotassium Channels, Inwardly RectifyingERADproteasomeprotein quality controlROMKSaccharomyces cerevisiaeType II Bartter Syndromeyeast

Identifiers

PMID28723237
PMCPMC5786258

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.