Evidence map›Paper›PMID 28723101›Full record

ReviewChemical reviews2017

Virus-Derived Peptides for Clinical Applications.

Mingying Yang, Kegan Sunderland, Chuanbin Mao

Open access · greenAbstract readReview
In one paragraph

Review in Chemical reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 66 citations in OpenAlex.

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  20. An overview of functional nanoparticles as novel emerging antiviral therapeutic agents.Materials science & engineering. C, Materials for biological applications · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Mingying YangInstitute of Applied Bioresource Research, College of Animal Science, Zhejiang University , Yuhangtang Road 866, Hangzhou 310058, China.
Kegan SunderlandDepartment of Chemistry & Biochemistry, Stephenson Life Science Research Center, University of Oklahoma , 101 Stephenson Parkway, Norman, Oklahoma 73019, United States.
Chuanbin MaoDepartment of Chemistry & Biochemistry, Stephenson Life Science Research Center, University of Oklahoma , 101 Stephenson Parkway, Norman, Oklahoma 73019, United States.ORCID http://orcid.org/0000-0002-8142-3659
Zhejiang University · CNUniversity of Oklahoma · US

Funding

Virus-based nanoparticles for detecting breast cancer biomarkersR01EB021339 · NIBIB · UNIVERSITY OF OKLAHOMA · PI CAO, BINRUI · 2016 to 2019
$1.4M
Selective tumor inhibition by tumor-homing angiogenesis-suppressing nanofibersR21CA200504 · NCI · UNIVERSITY OF OKLAHOMA · PI MAO, CHUANBIN · 2015 to 2016
$361k
Hiring Non-toxic Virus Nanoparticles to Count Cancer Biomarker MoleculesR21CA195607 · NCI · UNIVERSITY OF OKLAHOMA · PI MAO, CHUANBIN · 2015 to 2016
$359k
Investigation of metabolites related to manganese exposureF31ES027304 · NIEHS · UNIVERSITY OF WASHINGTON · PI BAKER, MARISSA GAYL · 2016 to 2017
$61k
NCI NIH HHS R21 CA195607NCI NIH HHS R21 CA200504NIBIB NIH HHS R01 EB021339NIEHS NIH HHS 27304C2054
6 · The paper itself

Abstract

Novel affinity agents with high specificity are needed to make progress in disease diagnosis and therapy. Over the last several years, peptides have been considered to have fundamental benefits over other affinity agents, such as antibodies, due to their fast blood clearance, low immunogenicity, rapid tissue penetration, and reproducible chemical synthesis. These features make peptides ideal affinity agents for applications in disease diagnostics and therapeutics for a wide variety of afflictions. Virus-derived peptide techniques provide a rapid, robust, and high-throughput way to identify organism-targeting peptides with high affinity and selectivity. Here, we will review viral peptide display techniques, how these techniques have been utilized to select new organism-targeting peptides, and their numerous biomedical applications with an emphasis on targeted imaging, diagnosis, and therapeutic techniques. In the future, these virus-derived peptides may be used as common diagnosis and therapeutics tools in local clinics.

Indexed as

Molecular Targeted TherapyHumansPeptidesSubstrate SpecificityVirusesPeptides

Identifiers

PMID28723101
PMCPMC5894882
OpenAlexW2736553453

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.