Evidence map›Paper›PMID 28722754›Full record

ArticlePhotochemistry and photobiology2017

Prabhu P Mohapatra, Callistus O Chiemezie, Arina Kligman, Michele M Kim, Theresa M Busch, Timothy C Zhu, Alexander Greer

Abstract read
In one paragraph

Article in Photochemistry and photobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Prabhu P MohapatraDepartment of Chemistry, Brooklyn College, Brooklyn, NY.
Callistus O ChiemezieDepartment of Chemistry, Brooklyn College, Brooklyn, NY.
Arina KligmanDepartment of Chemistry, Brooklyn College, Brooklyn, NY.
Michele M KimDepartment of Radiation Oncology, University of Pennsylvania, Perelman Center for Advanced Medicine, Philadelphia, PA.
Theresa M BuschDepartment of Radiation Oncology, University of Pennsylvania, Perelman Center for Advanced Medicine, Philadelphia, PA.
Timothy C ZhuDepartment of Radiation Oncology, University of Pennsylvania, Perelman Center for Advanced Medicine, Philadelphia, PA.
Alexander GreerDepartment of Chemistry, Brooklyn College, Brooklyn, NY.

Funding

TUMOR HYPOXIA, PHOTOSENSITIZER, VASCULARITY AND PDTP01CA087971 · NCI · UNIVERSITY OF PENNSYLVANIA · PI BUSCH, THERESA M, CENGEL, KEITH A · 2001 to 2019
$24.8M
Image-guided treatment planning for pleural Photodynamic TherapyR01CA154562 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ZHU, TIMOTHY C. · 2012 to 2016
$1.6M
NCI NIH HHS P01 CA087971NCI NIH HHS R01 CA154562
6 · The paper itself

Abstract

Intralipid is a lipid emulsion used in photodynamic therapy (PDT) for its light scattering and tissue-simulating properties. The purpose of this study is to determine whether or not Intralipid undergoes photooxidation, and we have carried out an Intralipid peroxide trapping study using a series of phosphines [2'-dicyclohexylphosphino-2,6-dimethoxy-1,1'-biphenyl-3-sulfonate, 3-(diphenylphosphino)benzenesulfonate, triphenylphosphine-3,3',3''-trisulfonate and triphenylphosphine]. Our new findings are as follows: (1) An oxygen atom is transferred from Intralipid peroxide to the phosphine traps in the dark, after the photooxidation of Intralipid. 3-(Diphenylphosphino)benzenesulfonate is the most suitable trap in the series owing to a balance of nucleophilicity and water solubility. (2) Phosphine trapping and monitoring by

Indexed as

LightPhosphorusDrug StabilityEmulsionsLipidsMagnetic Resonance SpectroscopyMolecular StructureOxidation-ReductionPeroxidesPhosphinesPhospholipidsSolubilitySoybean OilStereoisomerismEmulsionsLipidsPeroxidesphosphinePhosphinesPhospholipidsPhosphorusSoybean Oilsoybean oil, phospholipid emulsion

Identifiers

PMID28722754
PMCPMC12175620

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.