ArticleThe American journal of tropical medicine and hygiene2017
High Iron Levels Are Associated with Increased Malaria Risk in Infants during the First Year of Life in Benin.
Article in The American journal of tropical medicine and hygiene, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 23 citations in OpenAlex.
- Associations Between Climate-Sensitive Nutrients, Clinical Malaria, and Anaemia Among Young Children in Rural Burkina Faso: An Analysis of Baseline Data From a Cluster-Randomised Controlled Trial.Tropical medicine & international health : TM & IH · 2026Trial
- Effect of dietary intervention on the prevalence of asymptomatic malaria among 6-18-month-old children in rural Malawi.Malaria journal · 2023Trial
- Associations of maternal iron deficiency with malaria infection in a cohort of pregnant Papua New Guinean women.Malaria journal · 2022Trial
- Risk of malaria in young children after periconceptional iron supplementation.Maternal & child nutrition · 2021Trial
- Safe and effective delivery of supplemental iron to healthy adults: a two-phase, randomized, double-blind trial - the safe iron study.Frontiers in nutrition · 2023Article
- Universal iron supplementation: the best strategy to tackle childhood anaemia in malaria-endemic countries?Wellcome open research · 2023Review
- Article
- Gut Microbiome Alterations following Postnatal Iron Supplementation Depend on Iron Form and Persist into Adulthood.Nutrients · 2022Article
- Update of pre- and postnatal iron supplementation in malaria endemic settings.Seminars in perinatology · 2019Review
- Early Childhood Anemia in a Birth Cohort in Coastal Kenya: Links to Infection and Nutrition.The American journal of tropical medicine and hygiene · 2019Article
- Iron Status and Associated Malaria Risk Among African Children.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019Observational
- Blood lead level in infants and subsequent risk of malaria: A prospective cohort study in Benin, Sub-Saharan Africa.PloS one · 2019Article
- Malaria causes long-term effects on markers of iron status in children: a critical assessment of existing clinical and epidemiological tools.Malaria journal · 2018Article
- How Eliminating Malaria May Also Prevent Iron Deficiency in African Children.Pharmaceuticals (Basel, Switzerland) · 2018Review
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The World Health Organization (WHO) estimates that 40% of children in low-income countries are anemic. Therefore, iron supplements are recommended by WHO in areas with high anemia rates. However, some studies have set into question the benefits of iron supplementation in malaria-endemic regions. In Benin, a west African country with high prevalence of anemia and malaria, no iron supplements are given systematically to infants so far despite the WHO recommendations. In this context, we wanted to investigate the effect of iron levels during the first year of life on malarial risk in Benin considering complementary risk factors. We followed 400 women and their offspring between January 2010 and June 2012 in Allada (Benin). Environmental, obstetric, and numerous clinical, maternal, and infant risk factors were considered. In multilevel models, high iron levels were significantly associated with the risk of a positive blood smear (adjusted odds ratio = 2.90,
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