Evidence map›Paper›PMID 28722017›Full record

ArticleImmunology and cell biology2017

The role of age-related T-cell differentiation in patients with renal replacement therapy.

Matthias Schaier, Angele Leick, Lorenz Uhlmann, Florian Kälble, Volker Eckstein, Anthony Ho, Stefan Meuer, Karsten Mahnke, Claudia Sommerer, Martin Zeier and 1 more

Abstract read
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In one paragraph

Article in Immunology and cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Age-Related Risk After Kidney Transplantation: A Comprehensive Analysis of Infection Burden, Graft Outcomes, and Mortality.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  2. Article
  3. Article
  4. Sex-specific differences in ICOSClinical and experimental medicine · 2024
    Article
  5. Article
  6. Impaired Differentiation of Highly Proliferative ICOSInternational journal of molecular sciences · 2021
    Article
  7. Early Humoral Responses of Hemodialysis Patients after COVID-19 Vaccination with BNT162b2.Clinical journal of the American Society of Nephrology : CJASN · 2021
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Matthias SchaierDepartment of Medicine I (Nephrology), University of Heidelberg, Heidelberg, Germany.
Angele LeickDepartment of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany.
Lorenz UhlmannInstitute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany.
Florian KälbleDepartment of Medicine I (Nephrology), University of Heidelberg, Heidelberg, Germany.
Volker EcksteinDepartment of Medicine V (Hematology), University of Heidelberg, Heidelberg, Germany.
Anthony HoDepartment of Medicine V (Hematology), University of Heidelberg, Heidelberg, Germany.
Stefan MeuerInstitute of Immunology, University of Heidelberg, Heidelberg, Germany.
Karsten MahnkeDepartment of Dermatology, University of Heidelberg, Heidelberg, Germany.
Claudia SommererDepartment of Medicine I (Nephrology), University of Heidelberg, Heidelberg, Germany.
Martin ZeierDepartment of Medicine I (Nephrology), University of Heidelberg, Heidelberg, Germany.
Andrea SteinbornDepartment of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dialysis patients have deficiencies regarding the generation of immune responses and show an increased susceptibility for infections. Persisting uremic conditions are made responsible for the increased aging of their immune system. In this study, we analyzed whether age-related differences in the differentiation of both recent-thymic-emigrant-(RTE)-regulatory (Tregs) and RTE-responder T cells (Tresps) into CD31

Indexed as

Cell DifferentiationRenal DialysisAdolescentAdultAgedAged, 80 and overAgingCells, CulturedHumansImmunologic MemoryMaleMiddle AgedPlatelet Endothelial Cell Adhesion Molecule-1Renal Replacement TherapyRiskT-Lymphocytes, RegulatoryPlatelet Endothelial Cell Adhesion Molecule-1

Identifiers

PMID28722017

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.