Evidence map›Paper›PMID 28721647›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2019

Rubidium-82 PET imaging is feasible in a rat myocardial infarction model.

Adam Ali Ghotbi, Andreas Clemmensen, Kasper Kyhl, Bjarke Follin, Philip Hasbak, Thomas Engstrøm, Rasmus Sejersten Ripa, Andreas Kjaer

Abstract read
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. [Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  3. [Diagnostics (Basel, Switzerland) · 2023
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. A good beginning with an uncertain future.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Adam Ali GhotbiDepartment of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark. adamghotbi@gmail.com.
Andreas ClemmensenDepartment of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Kasper KyhlDepartment of Cardiology, The Heart Center, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark.
Bjarke FollinDepartment of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Philip HasbakDepartment of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Thomas EngstrømDepartment of Cardiology, The Heart Center, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark.
Rasmus Sejersten RipaDepartment of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Andreas KjaerDepartment of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSmall-animal myocardial infarct models are frequently used in the assessment of new cardioprotective strategies. A validated quantification of perfusion using a non-cyclotron-dependent PET tracer would be of importance in monitoring response to therapy. We tested whether myocardial PET perfusion imaging is feasible with Rubidium-82 (

methods18 Sprague-Dawley rats underwent permanent coronary artery ligation (infarct group), and 11 rats underwent ischemia-reperfusion (reperfusion group) procedure.

resultsFollow-up global

conclusion

Indexed as

Myocardial Perfusion ImagingPositron-Emission TomographyRubidium RadioisotopesAnimalsDisease Models, AnimalFeasibility StudiesMagnetic Resonance ImagingMaleMyocardial InfarctionRatsRats, Sprague-DawleyRubidium-82Rubidium Radioisotopesinfarctionmagnetic resonanceperfusion imagingrat myocardiumrubidium-82 PETSmall-animal heart

Identifiers

PMID28721647
PMCPMC6517336

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.