ArticleNPJ aging and mechanisms of disease2017
Age-related circadian disorganization caused by sympathetic dysfunction in peripheral clock regulation.
Article in NPJ aging and mechanisms of disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05482711 (Assessment of Fuel Utilization and Circadian Rhythms in Overweight, Older Adults Following Time Restricted Eating - Phase 2), which is not on this map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessment of Fuel Utilization and Circadian Rhythms in Overweight, Older Adults Following Time Restricted Eating - Phase 2 (FAR Phase 2)
Who cites it
29 citing papers in PubMed, 64 citations in OpenAlex.
- Investigating circadian clock gene expression in human tendon biopsies from acute exercise and immobilization studies.European journal of applied physiology · 2019Trial
- Additive framework of hormonal waves accounts for species and age differences in circadian intraocular pressure rhythm.Npj biological timing and sleep · 2026Article
- Internal desynchrony of the hepatic circadian system with dissociated systemic rhythms in middle-aged mice under social jet lag-like conditions.Scientific reports · 2026Article
- Multifaceted dynamics of circadian timing system influence aging and longevity.Biogerontology · 2025Review
- A minimal model of peripheral clocks reveals differential circadian re-entrainment in aging.Chaos (Woodbury, N.Y.) · 2023Article
- Age-related changes in circadian regulation of the human plasma lipidome.Communications biology · 2023Article
- Beta 2 Adrenergic Receptor Selective Antagonist Enhances Mechanically Stimulated Bone Anabolism in Aged Mice.JBMR plus · 2023Article
- Age and Chronodisruption in Mouse Heart: Effect of the NLRP3 Inflammasome and Melatonin Therapy.International journal of molecular sciences · 2022Article
- Oak extracts modulate circadian rhythms of clock gene expression in vitro and wheel-running activity in mice.Sleep and biological rhythms · 2022Article
- Wheel-Running Facilitates Phase Advances in Locomotor and Peripheral Circadian Rhythm in Social Jet Lag Model Mice.Frontiers in physiology · 2022Article
- Assessing Sex-Specific Circadian, Metabolic, and Cognitive Phenotypes in the AβPP/PS1 and APPNL-F/NL-F Models of Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2022Article
- Review
- The circadian clock and diseases of the skin.FEBS letters · 2021Review
- The circadian clock and metabolic homeostasis: entangled networks.Cellular and molecular life sciences : CMLS · 2021Review
- β-Lactolin Reduces Age-Related Inflammation and Cognitive Decline.Frontiers in nutrition · 2021Article
- Chrono-Nutrition Has Potential in Preventing Age-Related Muscle Loss and Dysfunction.Frontiers in neuroscience · 2021Review
- Dissecting the Roles of the Autonomic Nervous System and Physical Activity on Circadian Heart Rate Fluctuations in Mice.Frontiers in physiology · 2021Article
- Cardiolipin Synthesis in Skeletal Muscle Is Rhythmic and Modifiable by Age and Diet.Oxidative medicine and cellular longevity · 2020Article
- A standardized method to assess the endogenous activity and the light-response of the retinal clock in mammals.Molecular vision · 2020Article
- Aging and the clock: Perspective from flies to humans.The European journal of neuroscience · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ability of the circadian clock to adapt to environmental changes is critical for maintaining homeostasis, preventing disease, and limiting the detrimental effects of aging. To date, little is known about age-related changes in the entrainment of peripheral clocks to external cues. We therefore evaluated the ability of the peripheral clocks of the kidney, liver, and submandibular gland to be entrained by external stimuli including light, food, stress, and exercise in young versus aged mice using
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.