ArticleNPJ biofilms and microbiomes2015
Bacterial attachment and biofilm formation on surfaces are reduced by small-diameter nanoscale pores: how small is small enough?
Article in NPJ biofilms and microbiomes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
64 citing papers in PubMed.
- Comparative Assessment of Fungal Biofilm Development on PEEK and PDMS Biomaterials and the Antifungal Potential of TiOMaterials (Basel, Switzerland) · 2026Article
- Antibacterial surface engineering: bioinspiration from leaves to medical devices.RSC applied interfaces · 2026Review
- Inter-Crystal Spacing of Implantable Polymeric Surfaces as a Key Suppressor of Microbial Adhesion.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Diblock Copolymer Engineered Swim Bladder Membrane Enables Spatiotemporal Synchronized Defense and Pro-Healing in Challenging Soft Tissue Regeneration.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Repurposing trifluridine as an anti-Staphylococcus aureus agent targeting virulence factor staphyloxanthin and attachment genes.Scientific reports · 2026Article
- Synthesis and multi-technique structural characterization of trimetallic oxide nanocomposites for environmental and medicinal applications.Scientific reports · 2026Article
- Spray Coating Oxidized Graphene-Based Materials Makes Polyurethane Surfaces Antibacterial and Biocompatible: A Promising Approach for Medical Devices.ACS applied materials & interfaces · 2026Article
- Selective Trapping of Bacteria in Porous Media by Cell Length.Integrative and comparative biology · 2026Article
- Biological and Physicochemical Characterization of Biodegradable Aliphatic Polyesters with Copper Deposited by Magnetron Sputtering.Materials (Basel, Switzerland) · 2025Article
- Efficiency, Microbial Communities, and Nitrogen Metabolism in Denitrification Biological Filter: Insights into Varied Pore Ceramsite Media.Microorganisms · 2025Article
- Bacterial accumulation in intestinal folds induced by physical and biological factors.BMC biology · 2024Article
- Impact of nanoscale silicon dioxide coating of stainless-steel surfaces on Listeria monocytogenes.Folia microbiologica · 2024Article
- All-in-one porous membrane enables full protection in guided bone regeneration.Nature communications · 2024Article
- A comprehensive comparison of biofilm formation and capsule production for bacterial survival on hospital surfaces.Biofilm · 2023Article
- Blue 405 nm LED light effectively inactivates bacterial pathogens on substrates and packaging materials used in food processing.Scientific reports · 2023Article
- Numerical and experimental investigation of multi-species bacterial co-aggregation.Scientific reports · 2023Article
- Ficin-Cyclodextrin-Based Docking Nanoarchitectonics of Self-Propelled Nanomotors for Bacterial Biofilm Eradication.Chemistry of materials : a publication of the American Chemical Society · 2023Article
- Anodized Nanostructured 316L Stainless Steel Enhances Osteoblast Functions and Exhibits Anti-Fouling Properties.ACS biomaterials science & engineering · 2023Article
- Overview of strategies to improve the antibacterial property of dental implants.Frontiers in bioengineering and biotechnology · 2023Review
- Multi-functional approach in the design of smart surfaces to mitigate bacterial infections: a review.Frontiers in cellular and infection microbiology · 2023Review
4 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
BACKGROUND/
objectivesPrevention of biofilm formation by bacteria is of critical importance to areas that directly affect human health and life including medicine, dentistry, food processing and water treatment. This work showcases an effective and affordable solution for reducing attachment and biofilm formation by several pathogenic bacteria commonly associated with foodborne illnesses and medical infections.
methodsOur approach exploits anodisation to create alumina surfaces with cylindrical nanopores with diameters ranging from 15 to 100 nm, perpendicular to the surface. The anodic surfaces were evaluated for attachment by
resultsWe found that anodic alumina surfaces with pore diameters of 15 and 25 nm were able to effectively minimise bacterial attachment or biofilm formation by all the microorganisms tested. Using a predictive physicochemical approach on the basis of the extended Derjaguin and Landau, Verwey and Overbeek (XDLVO) theory, we attributed the observed effects largely to the repulsive forces, primarily electrostatic and acid-base forces, which were greatly enhanced by the large surface area originating from the high density, small-diameter pores. We also demonstrate how this predictive approach could be used to optimise different elements of surface topography, particularly pore diameter and density, for further enhancing the observed bacteria-repelling effects.
conclusionsWe demonstrate that anodic nanoporous surfaces can effectively reduce bacterial attachment. These findings are expected to have immediate, far-reaching implications and commercial applications, primarily in health care and the food industry.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.