ArticleCancer management and research2017
Chemotherapy-associated paronychia treated with 2% povidone-iodine: a series of cases.
Article in Cancer management and research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- A randomised controlled trial of interventions for taxane-induced nail toxicity in women with early breast cancer.Scientific reports · 2022Trial
- Multidisciplinary Management of Severe Taxane-Induced Nail Toxicity in a Breast Cancer Patient.Cancer management and research · 2026Article
- Cross-Sectional Analysis of Paronychias in the National Electronic Injury Surveillance System 1999-2018.Skin appendage disorders · 2022Article
- The Effect of Nail Lacquer on Taxane-Induced Nail Changes in Women With Breast Cancer.Breast cancer : basic and clinical research · 2020Article
- Dermatologic conditions in women receiving systemic cancer therapy.International journal of women's dermatology · 2019Review
- Are topical beta-blockers really effective "in real life" for targeted therapy-induced paronychia.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Article
- Systemic Drug-induced Chronic Paronychia and Periungual Pyogenic Granuloma.Indian dermatology online journalReview
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNail changes are known to occur during the use of chemotherapy for a variety of malignancies, particularly those treated with taxanes and EGFR inhibitors. There are currently no actively recruiting prospective clinical trials investigating potential treatments. There are also no US Food and Drug Administration-approved medical treatments for chemotherapy-associated paronychia and no consensus on the best way to treat these common chemotherapy-induced events.
methodsA retrospective review of all cases presenting to a single dermatology private practice from June 2016 to January 2017 identified nine patients with chemotherapy-associated paronychia seeking treatment. Each patient was prescribed a topical solution comprised of 2% povidone-iodine in a dimethylsulfoxide vehicle that was prepared by a licensed compounding pharmacy. Patients were seen at 3 week and 6 week follow-up visits.
resultsAll 9/9 patients demonstrated complete or partial resolution. The number of nails involved for each patient ranged from 4-12. There were a total of 58 nails affected in the case series, and 44/58 (76%) resolved overall. The treatment was well tolerated.
conclusionThe topical povidone-iodine/dimethylsufoxide solution described is very effective in alleviating the signs and symptoms of paronychia associated with chemotherapy. This novel combination warrants further investigation in randomized, controlled trials to further elucidate its clinical utility.
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