Evidence map›Paper›PMID 28721063›Full record

Observational studyVascular health and risk management2017

Annual deterioration of renal function in hypertensive patients with and without diabetes.

Jorge Polonia, André Azevedo, Miguel Monte, José A Silva, Susana Bertoquini

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Vascular health and risk management, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Aspects of renal function and renal artery anatomy as indications for renal denervation.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Review
  4. Ultra-long-term efficacy and safety of catheter-based renal denervation in resistant hypertension: 10-year follow-up outcomes.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
    Article
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  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jorge PoloniaDepartment of Medicine, CINTESIS, Faculty of Medicine of Porto, University of Porto, Porto, Portugal.
André AzevedoDepartment of Medicine, CINTESIS, Faculty of Medicine of Porto, University of Porto, Porto, Portugal.
Miguel MonteDepartment of Medicine, CINTESIS, Faculty of Medicine of Porto, University of Porto, Porto, Portugal.
José A SilvaBlood Pressure Unit, Hospital Pedro Hispano, Matosinhos, Portugal.
Susana BertoquiniDepartment of Medicine, CINTESIS, Faculty of Medicine of Porto, University of Porto, Porto, Portugal.
Universidade do Porto · PTHospital Pedro Hispano · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) complicates hypertension and diabetes. Knowledge of the deterioration rate of CKD may anticipate adjustment of therapies with renal elimination. This study evaluates the rate of annual deterioration of renal function in hypertensive patients either with type 2 diabetes (DM2) or without it (non-DM) followed for 5 years and relates it with blood pressure (BP) and glycemic control. MATERIALS AND

methodsOut of a total of 1924 patients, 1023 patients (594 non-DM and 429 DM2, 53% female, aged 62.1±10.2 years) were evaluated over 5 years for the annual evolution of renal function (estimated glomerular filtration rate [eGFR], Modification of Diet in Renal Disease) ambulatory 24-hour blood pressure and metabolic parameters, corresponding to the analysis of 2378 patient-years.

resultsDM2 and non-DM did not differ for age, mean 24-hour BP levels, nighttime BP, albuminuria, and body mass index. DM2 versus non-DM showed a higher (

conclusionProgressive deterioration of renal function each year is frequent in hypertensive diabetic and non-diabetic patients. Beyond aging, this is particularly dependent on BP control particularly at nighttime, on drug therapy, and on highly abnormal glucose control.

Indexed as

Glomerular Filtration RateAgedAge FactorsAlbuminuriaAntihypertensive AgentsBiomarkersBlood GlucoseBlood PressureBlood Pressure Monitoring, AmbulatoryChi-Square DistributionCircadian RhythmDiabetes Mellitus, Type 2Diabetic NephropathiesDisease ProgressionFemaleGlycated HemoglobinAntihypertensive AgentsBiomarkersBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanHypoglycemic Agentsadultsannual deteriorationcaucasianschronic kidney diseasediabetesdiabetes type 2hypertensionrenal function

Identifiers

PMID28721063
PMCPMC5498504
OpenAlexW2663448857

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.