Evidence map›Paper›PMID 28721032›Full record

ArticleClinical interventions in aging2017

Young Chul Youn, Jae-Won Jang, Su-Hyun Han, HyeRyoun Kim, Ju-Won Seok, Jun Soo Byun, Kwang-Yeol Park, Seong Soo A An, In Kook Chun, SangYun Kim

Open access · goldAbstract read
In one paragraph

Article in Clinical interventions in aging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Advances in GPCR-Targeted PET Radiotracer Patents (2020-2025).Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Review
  4. Early-onset Alzheimer Disease and Its Variants.Continuum (Minneapolis, Minn.) · 2019
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Young Chul YounDepartment of Neurology, Chung-Ang University College of Medicine, Seoul.
Jae-Won JangDepartment of Neurology, Kangwon National University Hospital.
Su-Hyun HanDepartment of Neurology, Chung-Ang University College of Medicine, Seoul.
HyeRyoun KimDepartment of Laboratory Medicine.
Ju-Won SeokDepartment of Nuclear Medicine.
Jun Soo ByunDepartment of Radiology, Chung-Ang University College of Medicine.
Kwang-Yeol ParkDepartment of Neurology, Chung-Ang University College of Medicine, Seoul.
Seong Soo A AnCollege of Bionano Technology, Gachon Bionano Research Institute, Gachon University.
In Kook ChunDepartment of Nuclear Medicine, Kangwon National University Hospital.
SangYun KimDepartment of Neurology, Seoul National University Bundang Hospital and Seoul National University College of Medicine, Gyeonggi-do, Republic of Korea.
Chung-Ang University · KRKangwon National University Hospital · KRGachon University · KRSeoul National University Bundang Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEarly-onset Alzheimer's disease (EOAD) has a different pathologic burden and clinical features compared with late-onset Alzheimer's disease (LOAD). We examined the effects of age at onset on the burden and distribution of β-amyloid in patients with EOAD, in whom well-characterized mutations associated with Alzheimer's disease were absent.

methodsWe genotyped

resultsPatients with EOAD exhibited higher

conclusionDistribution of amyloid deposition in EOAD outside the context of genetic mutations topographically showed some differences from that in LOAD.

Indexed as

Age of OnsetAgedAlzheimer DiseaseAmyloid beta-PeptidesAmyloid beta-Protein PrecursorAniline CompoundsApolipoproteins EBasal GangliaBenzothiazolesFemaleGenotypeHumansMaleMiddle AgedMutationPositron-Emission Tomography2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazoleAmyloid beta-PeptidesAmyloid beta-Protein PrecursorAniline CompoundsApoE protein, humanApolipoproteins EAPP protein, humanBenzothiazolesPresenilin-1Presenilin-2PSEN1 protein, humanPSEN2 protein, humanThiazolesAlzheimer’s diseaseamyloidamyloid PETbasal gangliaearly-onset Alzheimer’s diseasePittsburgh compound B

Identifiers

PMID28721032
PMCPMC5500536
OpenAlexW2725836336

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.