ArticleClinical interventions in aging2017
Operationalizing a frailty index using routine blood and urine tests.
Article in Clinical interventions in aging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The frailty index based on laboratory test data as a tool to investigate the impact of frailty on health outcomes: a systematic review and meta-analysis.Age and ageing · 2023Pooled it
- Laboratory frailty index in pancreaticoduodenectomy: short-term safety and long-term prognosis.Surgery today · 2026Article
- Development of a laboratory-based frailty index for risk prediction in elderly trauma patients with hip fractures.GeroScience · 2026Article
- Frailty assessment in perioperative geriatric patients: a narrative review.Anesthesia and pain medicine · 2026Review
- Association Between the Frailty Index Based on Laboratory Tests and All-Cause Mortality in Hospitalized Older Adults: Retrospective Cohort Study.JMIR aging · 2025Article
- Investigating aging trajectories and determinants in Northern Italy through the Novara cohort study.Scientific reports · 2025Article
- FI-Lab predicts all-cause mortality, but not successful rehabilitation, among patients aged 65 and older after hip or pelvic fracture.Frontiers in medicine · 2025Article
- Article
- [Treatment response and complications of older patients with ANCA(antineutrophil cytoplasmatic antibody)-associated vasculitis].Zeitschrift fur Gerontologie und Geriatrie · 2023Article
- The Role of Surgical Prehabilitation During the COVID-19 Pandemic and Beyond.Physical medicine and rehabilitation clinics of North America · 2023Review
- Prognostic significance of frailty in hospitalized elderly patients with community-acquired pneumonia: a retrospective cohort study.BMC geriatrics · 2023Article
- A novel easy-to-use index to predict institutionalization and death in older population - a 10-year population-based follow-up study.BMC geriatrics · 2023Article
- Prognostic significance of frailty status in patients with primary lung cancer.BMC geriatrics · 2023Article
- Association between a Frailty Index from Common Laboratory Values and Vital Signs (FI-LAB) and Hospital and Post-Hospital Outcomes in Veterans with COVID-19 Infection.The journal of nutrition, health & aging · 2023Article
- Paracetamol dosing in hospital and on discharge for older people who are frail or have low body weight.British journal of clinical pharmacology · 2022Observational
- A frailty index based on routine laboratory data predicts increased risk of mortality in Chinese community-dwelling adults aged over 55 years: a five-year prospective study.BMC geriatrics · 2022Article
- Impact of preoperative laboratory frailty index on mortality and clinical outcomes in older surgical patients with cancer.Scientific reports · 2022Article
- Frailty indices based on self-report, blood-based biomarkers and examination-based data in the Canadian Longitudinal Study on Aging.Age and ageing · 2022Article
- Frailty index based on laboratory tests improves prediction of short-and long-term mortality in patients with critical acute myocardial infarction.Frontiers in medicine · 2022Article
- A Simple Risk Score Based on Routine Clinical Parameters Can Predict Frailty in Hospitalized Heart Failure Patients.Journal of clinical medicine · 2021Article
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundUncomplicated frailty instruments are desirable for use in a busy clinical setting. The aim of this study was to operationalize a frailty index (FI) from routine blood and urine tests, and to evaluate the properties of this FI compared to other frailty instruments. MATERIALS AND
methodsWe conducted a secondary analysis of a prospective cohort study on 306 patients aged ≥65 years hospitalized on geriatric wards. An FI comprising 22 routine blood parameters and one standard urine parameter (FI-Lab), a 50-item FI based on a comprehensive geriatric assessment (FI-CGA), a combined FI (FI-combined [items from the FI-Lab + others from the FI-CGA]), the Clinical Frailty Scale, rule-based frailty definition, and frailty phenotype were operationalized from data obtained during patients' hospital stays (ie, before discharge [baseline examination]). Follow-up data were obtained up to 1 year after the baseline examination.
resultsThe mean FI-Lab score was 0.34±15, with an upper limit of 0.74. The FI-Lab was correlated with all the other frailty instruments (all
conclusionThe FI-Lab showed key characteristics of an FI. The FI-Lab can be applied as a single frailty measure or in combination with/in addition to other frailty instruments.
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