Trial reportBehavioural neurology2017
Cerebral Reorganization in Subacute Stroke Survivors after Virtual Reality-Based Training: A Preliminary Study.
Trial report in Behavioural neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 45 citations in OpenAlex.
- 360° immersive virtual reality-based mirror therapy for upper extremity function and satisfaction among stroke patients: a randomized controlled trial.European journal of physical and rehabilitation medicine · 2024Trial
- Article
- The lateralized cerebellum: insights into motor, cognitive, and affective functioning across ages: a scoping review.Journal of neurology · 2025Article
- Effects of 3DVR-haptic simulation training on cognitive functions: a functional neuroimaging pilot study using swLORETA qEEG.Frontiers in human neuroscience · 2025Article
- Measuring Neuroplasticity in Response to Cardiovascular Exercise in People With Stroke: A Critical Perspective.Neurorehabilitation and neural repair · 2024Article
- Article
- Neurofunctional correlates of a neurorehabilitation system based on eye movements in chronic stroke impairment levels: A pilot study.Brain and behavior · 2023Article
- Sex differences in the neural underpinnings of unimanual and bimanual control in adults.Experimental brain research · 2023Article
- Aphasia improvement without logotherapy during motor neurorehabilitation of post-stroke hemiparesis using virtual reality or modified constraint-induced movement therapy: A retrospective cohort.NeuroRehabilitation · 2023Article
- Virtual reality-induced motor function of the upper extremity and brain activation in stroke: study protocol for a randomized controlled trial.Frontiers in neurology · 2023Article
- Graph analysis of cortical reorganization after virtual reality-based rehabilitation following stroke: a pilot randomized study.Frontiers in neurology · 2023Article
- A social VR-based collaborative exergame for rehabilitation: codesign, development and user study.Virtual reality · 2022Article
- Walking speed at the acute and subacute stroke stage: A descriptive meta-analysis.Frontiers in neurology · 2022Review
- The impact of acupuncture on neuroplasticity after ischemic stroke: a literature review and perspectives.Frontiers in cellular neuroscience · 2022Review
- Modern Rehabilitation Technologies of Patients with Motor Disorders at an Early Rehabilitation of Stroke (Review).Sovremennye tekhnologii v meditsine · 2022Review
- The Efficacy of Interlimb-Coordinated Intervention on Gait and Motor Function Recovery in Patients with Acute Stroke: A Multi-Center Randomized Controlled Trial Study Protocol.Brain sciences · 2021Article
- Neurophysiological Correlates of Cognition as Revealed by Virtual Reality: Delving the Brain with a Synergistic Approach.Brain sciences · 2021Review
- Virtual reality training improves dynamic balance in children with cerebral palsy.International journal of developmental disabilities · 2021Article
- Immersive Virtual Reality in Stroke Patients as a New Approach for Reducing Postural Disabilities and Falls Risk: A Case Series.Brain sciences · 2020Article
- Effects of Virtual Reality-Based Rehabilitation on Burned Hands: A Prospective, Randomized, Single-Blind Study.Journal of clinical medicine · 2020Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFunctional magnetic resonance imaging (fMRI) is a promising method for quantifying brain recovery and investigating the intervention-induced changes in corticomotor excitability after stroke. This study aimed to evaluate cortical reorganization subsequent to virtual reality-enhanced treadmill (VRET) training in subacute stroke survivors.
methodsEight participants with ischemic stroke underwent VRET for 5 sections per week and for 3 weeks. fMRI was conducted to quantify the activity of selected brain regions when the subject performed ankle dorsiflexion. Gait speed and clinical scales were also measured before and after intervention.
resultsIncreased activation in the primary sensorimotor cortex of the lesioned hemisphere and supplementary motor areas of both sides for the paretic foot (
conclusionsWe observed improved walking and increased activation in cortical regions of stroke survivors after VRET training. Moreover, the cortical recruitment was associated with better walking function. Our study suggests that cortical networks could be a site of plasticity, and their recruitment may be one mechanism of training-induced recovery of gait function in stroke. This trial is registered with ChiCTR-IOC-15006064.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.