Evidence map›Paper›PMID 28720883›Full record

ArticleScientific reports2017

Chronic high-sodium diet intake after weaning lead to neurogenic hypertension in adult Wistar rats.

Paula Magalhães Gomes, Renato Willian Martins Sá, Giovana Lopes Aguiar, Milede Hanner Saraiva Paes, Andréia Carvalho Alzamora, Wanderson Geraldo Lima, Lisandra Brandino de Oliveira, Sean David Stocker, Vagner Roberto Antunes, Leonardo M Cardoso

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Antihypertensive Effects of Aqueous Extract ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  9. Heliyon · 2021
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Paula Magalhães GomesDepartment of Biological Sciences, Institute of Exact and Biological Sciences and NUPEB, Federal University of Ouro Preto, Ouro Preto, (MG), Brazil.
Renato Willian Martins SáDepartment of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, (SP), Brazil.
Giovana Lopes AguiarDepartment of Biological Sciences, Institute of Exact and Biological Sciences and NUPEB, Federal University of Ouro Preto, Ouro Preto, (MG), Brazil.
Milede Hanner Saraiva PaesDepartment of Biological Sciences, Institute of Exact and Biological Sciences and NUPEB, Federal University of Ouro Preto, Ouro Preto, (MG), Brazil.
Andréia Carvalho AlzamoraDepartment of Biological Sciences, Institute of Exact and Biological Sciences and NUPEB, Federal University of Ouro Preto, Ouro Preto, (MG), Brazil.
Wanderson Geraldo LimaDepartment of Biological Sciences, Institute of Exact and Biological Sciences and NUPEB, Federal University of Ouro Preto, Ouro Preto, (MG), Brazil.
Lisandra Brandino de OliveiraDepartment of Biological Sciences, Institute of Exact and Biological Sciences and NUPEB, Federal University of Ouro Preto, Ouro Preto, (MG), Brazil.
Sean David StockerDepartment of Medicine, Division of Renal-Electrolyte, University of Pittsburgh School of Medicine, Pittsburgh, (PA), United States of America.
Vagner Roberto AntunesDepartment of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, (SP), Brazil.
Leonardo M CardosoDepartment of Biological Sciences, Institute of Exact and Biological Sciences and NUPEB, Federal University of Ouro Preto, Ouro Preto, (MG), Brazil. leomcardoso@gmail.com.
Universidade Federal de Ouro Preto · BRUniversidade de São Paulo · BRUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we investigated some mechanisms involved in sodium-dependent hypertension of rats exposed to chronic salt (NaCl) intake from weaning until adult age. Weaned male Wistar rats were placed under high (0.90% w/w, HS) or regular (0.27% w/w, Cont) sodium diets for 12 weeks. Water consumption, urine output and sodium excretion were higher in HS rats compared to control. Blood pressure (BP) was directly measured by the arterial catheter and found 13.8% higher in HS vs Cont rats. Ganglionic blockade with hexamethonium caused greater fall in the BP of HS rats (33%), and central antagonism of AT

Indexed as

AnimalsAntihypertensive AgentsBlood Pressure DeterminationHeart RateHexamethoniumHypertensionLosartanMalePotassiumRatsRats, WistarSodiumSodium Chloride, DietaryWeaningAntihypertensive AgentsHexamethoniumLosartanPotassiumSodiumSodium Chloride, Dietary

Identifiers

PMID28720883
PMCPMC5515999
OpenAlexW2734432184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.