ArticleScientific reports2017
Altered hippocampal volume and functional connectivity in males with Internet gaming disorder comparing to those with alcohol use disorder.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 7 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 7 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- The role of the cerebellum in internet gaming disorder-A systematic review.Addiction biology · 2023Pooled it
- Internet addiction-induced brain structure and function alterations: a systematic review and meta-analysis of voxel-based morphometry and resting-state functional connectivity studies.Brain imaging and behavior · 2023Pooled it
- Structural gray matter differences in Problematic Usage of the Internet: a systematic review and meta-analysis.Molecular psychiatry · 2022Pooled it
- Meta-analysis of structural and functional brain alterations in internet gaming disorder.Frontiers in psychiatry · 2022Pooled it
- Shared gray matter alterations in subtypes of addiction: a voxel-wise meta-analysis.Psychopharmacology · 2021Pooled it
- Structural and Functional Brain Abnormalities in Internet Gaming Disorder and Attention-Deficit/Hyperactivity Disorder: A Comparative Meta-Analysis.Frontiers in psychiatry · 2021Pooled it
- Shared gray matter alterations in individuals with diverse behavioral addictions: A voxel-wise meta-analysis.Journal of behavioral addictions · 2020Pooled it
- Network diffusion modeling predicts spatiotemporal gray matter alterations in internet gaming disorder.Psychological medicine · 2026Article
- Dynamic functional connectivity of the amygdala-hippocampal complex is associated with cognitive impairment in adolescents with Internet gaming disorder.Frontiers in psychiatry · 2025Article
- Investigating Therapeutic Targets for Alcohol Use Disorder: Pharmacological View of ClinicalTrials.gov Data.International journal of general medicine · 2025Review
- Alterations of gray matter asymmetry in internet gaming disorder.Scientific reports · 2024Article
- Regional brain activity of resting-state fMRI and auditory oddball ERP with multimodal approach in individuals with internet gaming disorder.Journal of behavioral addictions · 2023Article
- Mapping the neuroanatomical abnormalities in a phenotype of male compulsive rats.Behavioral and brain functions : BBF · 2023Article
- Altered Functional Connectivity of the Nucleus Accumbens and Amygdala in Cyber Addiction: A Resting State Functional Magnetic Resonance Imaging Study.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2023Article
- Interaction effects between smoking and internet gaming disorder on resting-state functional connectivity of the ventral tegmental area and hippocampus.Frontiers in neuroscience · 2023Article
- Opposing associations of Internet Use Disorder symptom domains with structural and functional organization of the striatum: A dimensional neuroimaging approach.Journal of behavioral addictions · 2022Article
- Common Gray Matter Reductions in Alcohol Use and Obsessive-Compulsive Disorders: A Meta-analysis.Biological psychiatry global open science · 2022Article
- Differentiating Individuals with and without Alcohol Use Disorder Using Resting-State fMRI Functional Connectivity of Reward Network, Neuropsychological Performance, and Impulsivity Measures.Behavioral sciences (Basel, Switzerland) · 2022Article
- Article
- Identifying Internet Addiction and Evaluating the Efficacy of Treatment Based on Functional Connectivity Density: A Machine Learning Study.Frontiers in neuroscience · 2021Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Internet gaming disorder (IGD) has been conceptualized as a behavioral addiction and shares clinical, neuropsychological, and personality characteristics with alcohol use disorder (AUD), but IGD dose not entail brain exposure to toxic agents, which renders it different from AUD. To achieve a clear understanding of the neurobiological features of IGD, we aimed to identify morphological and functional changes in IGD and compare them with those in AUD. Individuals with IGD showed larger volume in the hippocampus/amygdala and precuneus than healthy controls (HCs). The volume in the hippocampus positively correlated with the symptom severity of IGD. Moreover, functional connectivity analysis with the hippocampus/amygdala cluster revealed that the left ventromedial prefrontal cortex showed stronger functional connectivity in individuals with IGD compared to those with AUD. In contrast, individuals with AUD exhibited the smaller cerebellar volume and thinner medial frontal cortex than HCs. The volume in the cerebellum correlated with impaired working memory function as well as duration of illness in AUD group. Findings suggested that altered volume and functional connectivity in the hippocampus/amygdala in IGD might be associated with abnormally enhanced memory process of gaming-related cues, while abnormal cortical changes and cognitive impairments in AUD might be associated with neurotoxic effects of alcohol.
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