Evidence map›Paper›PMID 28720711›Full record

ArticleG3 (Bethesda, Md.)2017

Gene Expression Networks in the Murine Pulmonary Myocardium Provide Insight into the Pathobiology of Atrial Fibrillation.

Jordan K Boutilier, Rhonda L Taylor, Tracy Mann, Elyshia McNamara, Gary J Hoffman, Jacob Kenny, Rodney J Dilley, Peter Henry, Grant Morahan, Nigel G Laing and 1 more

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Jordan K BoutilierHarry Perkins Institute for Medical Research.
Rhonda L TaylorHarry Perkins Institute for Medical Research, rhonda.taylor@perkins.uwa.edu.au.
Tracy MannSchool of Biomedical Sciences, University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, 6009, Australia.
Elyshia McNamaraHarry Perkins Institute for Medical Research.
Gary J HoffmanSchool of Biomedical Sciences, University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, 6009, Australia.
Jacob KennySchool of Biomedical Sciences, University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, 6009, Australia.
Rodney J DilleyEar Sciences Centre, Faculty of Health and Medical Sciences, University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, 6009, Australia.
Peter HenrySchool of Biomedical Sciences, University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, 6009, Australia.
Grant MorahanHarry Perkins Institute for Medical Research.
Nigel G LaingHarry Perkins Institute for Medical Research.
Kristen J NowakHarry Perkins Institute for Medical Research.
Queen Elizabeth II Medical Centre · AUHarry Perkins Institute of Medical Research · AUUniversity of Western Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pulmonary myocardium is a muscular coat surrounding the pulmonary and caval veins. Although its definitive physiological function is unknown, it may have a pathological role as the source of ectopic beats initiating atrial fibrillation. How the pulmonary myocardium gains pacemaker function is not clearly defined, although recent evidence indicates that changed transcriptional gene expression networks are at fault. The gene expression profile of this distinct cell type

Indexed as

Gene Regulatory NetworksGenetic Predisposition to DiseaseAnimalsAtrial FibrillationBiomarkersCalciumChromosome MappingComputational BiologyDatabases, GeneticGene Expression ProfilingGenetic Association StudiesMAP Kinase Kinase KinasesMiceMolecular Sequence AnnotationPhenotypeProtein Serine-Threonine KinasesBiomarkersCalciumMAP Kinase Kinase KinasesProtein Serine-Threonine KinasesTNNI3K protein, humanatrial fibrillationeQTLgene networkpulmonary myocardium

Identifiers

PMID28720711
PMCPMC5592927
OpenAlexW2738524096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.