ReviewBMC medicine2017
Environmental/lifestyle factors in the pathogenesis and prevention of type 2 diabetes.
Review in BMC medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 350 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
350 citing papers in PubMed, 7 syntheses or guidelines pooled it, 717 citations in OpenAlex.
- Clinical guidelines on physical activity and exercise therapy for Chinese adults with type 2 diabetes: A clinical practice guideline from the Chinese Society of Endocrinology.Journal of sport and health science · 2026Guideline
- Meta-evolutionary exome analysis identifies novel type 2 diabetes mellitus genes in the UK Biobank and all of us.PLoS genetics · 2025Pooled it
- Time-Restricted Eating Improves Glycemic Control in Patients with Type 2 Diabetes: A Meta-Analysis and Systematic Review.International journal of molecular sciences · 2025Pooled it
- Umbrella Review of Systematic Reviews and Meta-Analyses on Consumption of Different Food Groups and Risk of Type 2 Diabetes Mellitus and Metabolic Syndrome.The Journal of nutrition · 2025Pooled it
- Pooled it
- The efficacy and potential mechanism of the acupuncture treatment for type 2 diabetes mellitus: A systematic review and meta-analysis of data from animal models.Frontiers in endocrinology · 2025Pooled it
- Effectiveness of Chickpeas on Blood Sugar: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Nutrients · 2023Pooled it
- Trial
- Comparative evaluation of dulaglutide alone vs. dulaglutide combined with probiotics on cardiovascular risk factors in T2DM.Hormones (Athens, Greece) · 2025Trial
- Self-initiated lifestyle changes during a fasting-mimicking diet programme in patients with type 2 diabetes: a mixed-methods study.BMC primary care · 2024Trial
- Trial
- The effect of a short-term ketogenic diet on exercise efficiency during graded exercise in healthy adults.Journal of the International Society of Sports Nutrition · 2023Trial
- Impact of a Low-Insulin-Stimulating Bread on Weight Development-A Real Life Randomised Controlled Trial.Nutrients · 2023Trial
- Association of glycemic control and chronic kidney disease with hospitalization in type 2 diabetes in a cross-sectional study in Region Halland.Scandinavian journal of primary health care · 2026Review
- Hospitalization in adults aged 75 years and older with type 2 diabetes: the role of kidney impairment and glycemic control.BMC geriatrics · 2026Article
- Baseline and longitudinal joint associations of alcohol consumption and obesity with diabetes risk: evaluating multiplicative and additive interactions.Diabetologia · 2026Article
- Joint effects of residential greenness and genetic susceptibility on type 2 diabetes: a prospective cohort study using satellite-derived Normalized Difference Vegetation Index.Life metabolism · 2026Article
- Prediabetes Subtypes with Divergent Iron Metabolism Profiles: A Cluster Analysis from Two Cohorts in the United States and China.Biological trace element research · 2026Article
- Associations between lifestyle, genetic liability for severe mental illness and risk of incident somatic illnesses.Translational psychiatry · 2026Article
- Association between elemental concentrations and chemotherapy-related acute adverse events in patients with nasopharyngeal carcinoma.Pharmacological reports : PR · 2026Article
290 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEnvironmental and lifestyle changes, in addition to the ageing of populations, are generally believed to account for the rapid global increase in type 2 diabetes prevalence and incidence in recent decades. DISCUSSION: In this review, we present a comprehensive overview of factors contributing to diabetes risk, including aspects of diet quality and quantity, little physical activity, increased monitor viewing time or sitting in general, exposure to noise or fine dust, short or disturbed sleep, smoking, stress and depression, and a low socioeconomic status. In general, these factors promote an increase in body mass index. Since loss of β-cell function is the ultimate cause of developing overt type 2 diabetes, environmental and lifestyle changes must have resulted in a higher risk of β-cell damage in those at genetic risk. Multiple mechanistic pathways may come into play.
conclusionsStrategies of diabetes prevention should aim at promoting a 'diabetes-protective lifestyle' whilst simultaneously enhancing the resistance of the human organism to pro-diabetic environmental and lifestyle factors. More research on diabetes-protective mechanisms seems warranted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.