ArticleBMC public health2017
A prolonged, community-wide cholera outbreak associated with drinking water contaminated by sewage in Kasese District, western Uganda.
Article in BMC public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers, 4 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Determinants of cholera among affected population of Ethiopia: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Associations of water quality with cholera in case-control studies: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Estimating the proportion of clinically suspected cholera cases that are true Vibrio cholerae infections: A systematic review and meta-analysis.PLoS medicine · 2023Pooled it
- Open defecation-free slippage and its associated factors in Ethiopia: a systematic review.Systematic reviews · 2020Pooled it
- Cholera Outbreaks in Low- and Middle-Income Countries in the Last Decade: A Systematic Review and Meta-Analysis.Microorganisms · 2024Review
- Attitude towards cholera vaccination and its related factors in Jordan amid the 2022 Middle East outbreak.BMC public health · 2024Article
- Pathways of exposure to Vibrio Cholerae in an urban informal settlement in Nairobi, Kenya.PLOS global public health · 2024Article
- Migration and Deposition Law of Pollutants in Urban Sewage Confluence Pipe Network from the Perspective of Ecology.Journal of environmental and public health · 2022Article
- Cholera outbreak caused by drinking unprotected well water contaminated with faeces from an open storm water drainage: Kampala City, Uganda, January 2019.BMC infectious diseases · 2021Article
- Refugee Settlements and Cholera Risks in Uganda, 2016-2019.The American journal of tropical medicine and hygiene · 2021Article
- Cholera risk in cities in Uganda: understanding cases and contacts centered strategy (3CS) for rapid cholera outbreak control.The Pan African medical journal · 2021Article
- Early detection of cholera epidemics to support control in fragile states: estimation of delays and potential epidemic sizes.BMC medicine · 2020Article
- A prolonged cholera outbreak caused by drinking contaminated stream water, Kyangwali refugee settlement, Hoima District, Western Uganda: 2018.Infectious diseases of poverty · 2020Article
- Article
- Epidemiology and antibiotic susceptibility of Vibrio cholerae associated with the 2017 outbreak in Kasese district, Uganda.BMC public health · 2019Article
- Review
- Evaluation of integrated disease surveillance and response (IDSR) core and support functions after the revitalisation of IDSR in Uganda from 2012 to 2016.BMC public health · 2019Article
- Uganda public health fellowship program's contribution to building a resilient and sustainable public health system in Uganda.Global health action · 2019Article
- A Cross-Cutting Approach to Surveillance and Laboratory Capacity as a Platform to Improve Health Security in Uganda.Health security · 2018Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
Abstract
backgroundIn May 2015, a cholera outbreak that had lasted 3 months and infected over 100 people was reported in Kasese District, Uganda, where multiple cholera outbreaks had occurred previously. We conducted an investigation to identify the mode of transmission to guide control measures.
methodsWe defined a suspected case as onset of acute watery diarrhoea from 1 February 2015 onwards in a Kasese resident. A confirmed case was a suspected case with Vibrio cholerae O1 El Tor, serotype Inaba cultured from a stool sample. We reviewed medical records to find cases. We conducted a case-control study to compare exposures among confirmed case-persons and asymptomatic controls, matched by village and age-group. We conducted environmental assessments. We tested water samples from the most affected area for total coliforms using the Most Probable Number (MPN) method.
resultsWe identified 183 suspected cases including 61 confirmed cases of Vibrio cholerae 01; serotype Inaba, with onset between February and July 2015. 2 case-persons died of cholera. The outbreak occurred in 80 villages and affected all age groups; the highest attack rate occurred in the 5-14 year age group (4.1/10,000). The outbreak started in Bwera Sub-County bordering the Democratic Republic of Congo and spread eastward through sustained community transmission. The first case-persons were involved in cross-border trading. The case-control study, which involved 49 confirmed cases and 201 controls, showed that 94% (46/49) of case-persons compared with 79% (160/201) of control-persons drank water without boiling or treatment (OR
conclusionsThis prolonged, community-wide cholera outbreak was associated with drinking water contaminated by faecal matter and cross-border trading. We recommended rigorous disposal of patients' faeces, chlorination of piped water, and boiling or treatment of drinking water. The outbreak stopped 6 weeks after these recommendations were implemented.
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