ArticleBMC cardiovascular disorders2017
Heterogeneity in national U.S. mortality trends within heart disease subgroups, 2000-2015.
Article in BMC cardiovascular disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
49 citing papers in PubMed, 72 citations in OpenAlex.
- Cardiovascular disease mortality trends in young adults aged 18-34 years, United States, 2000-2023.Annals of epidemiology · 2025Article
- Heart Disease Mortality in the United States, 1970 to 2022.Journal of the American Heart Association · 2025Article
- Applying a Bayesian spatiotemporal model to examine excess county-level cardiovascular disease death rates during the COVID-19 pandemic.American journal of epidemiology · 2025Article
- Trends in mortality due to ischemic heart diseases among patients with Alzheimer's disease in the United States from 1999 to 2020.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Prevalence, Disparities, and Mortality of Cardiovascular-Kidney-Metabolic Syndrome in US Adults, 2011-2018.The American journal of medicine · 2025Article
- Demographic and regional trends of pneumonia mortality in the United States, 1999 to 2022.Scientific reports · 2025Article
- Demographic Differences in Mortality in the District of ColumbiaJAMA network open · 2025Article
- Trends and regional variations in chronic ischemic heart disease and lung cancer-related mortality among American adults: Insights from retrospective CDC wonder analysis.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Global, regional, and national burdens of heart failure in adolescents and young adults aged 10-24 years from 1990 to 2021: an analysis of data from the Global Burden of Disease Study 2021.EClinicalMedicine · 2025Article
- Eligibility of Asian and European registry patients for phase III trials in heart failure with reduced ejection fraction.ESC heart failure · 2024Article
- Vicious cycle of vitamin BJournal of clinical biochemistry and nutrition · 2024Article
- Etiologic and demographic characteristics of syncope in children and adolescents: a nationwide population-based study in Korea.Translational pediatrics · 2024Article
- Trends in Mortality After Incident Hospitalization for Heart Failure Among Medicare Beneficiaries.JAMA network open · 2024Article
- Demographic trends of cardiorenal and heart failure deaths in the United States, 2011-2020.PloS one · 2024Article
- Causes of Death and Mortality Trends in Individuals with Thalassemia in the United States, 1999-2020.Journal of blood medicine · 2024Article
- The Science of Precision Prevention: Research Opportunities and Clinical Applications to Reduce Cardiovascular Health Disparities.JACC. Advances · 2024Article
- Impact of Social Vulnerability and Demographics on Ischemic Heart Disease Mortality in the United States.JACC. Advances · 2023Article
- Adverse Childhood Experiences, Social Isolation, Job Strain, and Cardiovascular Disease Mortality in U.S. Older Employees.Medicina (Kaunas, Lithuania) · 2023Article
- Implementing the National Heart, Lung, and Blood Institute's Strategic Vision in the Division of Cardiovascular Sciences-2022 Update.Circulation research · 2022Article
- Reviewing the Modern Therapeutical Options and the Outcomes of Sacubitril/Valsartan in Heart Failure.International journal of molecular sciences · 2022Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe long-term downward national U.S. trend in heart disease-related mortality slowed substantially during 2011-2014 before turning upward in 2015. Examining mortality trends in the major subgroups of heart disease may provide insight into potentially more targeted and effective prevention and treatment approaches to promote favorable trajectories. We examined national trends between 2000 and 2015 in mortality attributed to major heart disease subgroups including ischemic heart disease, heart failure, and all other types of heart disease.
methodsUsing the Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research (WONDER) data system, we determined national trends in age-standardized mortality rates attributed to ischemic heart disease, heart failure, and other heart diseases from January 1, 2000, to December 31, 2011, and from January 1, 2011, to December 31, 2015. Annual rate of changes in mortality attributed to ischemic heart disease, heart failure, and other heart diseases for 2000-2011 and 2011-2015 were compared.
resultsDeath attributed to ischemic heart disease declined from 2000 to 2015, but the rate of decline slowed from 4.96% (95% confidence interval 4.77%-5.15%) for 2000-2011 to 2.66% (2.00%-3.31%) for 2011-2015. In contrast, death attributed to heart failure and all other causes of heart disease declined from 2000 to 2011 at annual rates of 1.94% (1.77%-2.11%) and 0.64% (0.44%-0.82%) respectively, but increased from 2011 to 2015 at annual rates of 3.73% (3.21% 4.26%) and 1.89% (1.33-2.46%). Differences in 2000-2011 and 2011-2015 decline rates were statistically significant for all 3 endpoints overall, by sex, and all race/ethnicity groups except Asian/Pacific Islanders (heart failure only significant) and American Indian/Alaskan Natives.
conclusionsWhile the long-term decline in death attributed to heart disease slowed between 2011 and 2014 nationally before turning upward in 2015, heterogeneity existed in the trajectories attributed to heart disease subgroups, with ischemic heart disease mortality continuing to decline while death attributed to heart failure and other heart diseases switched from a downward to upward trend. While systematic efforts to prevent and treat ischemic heart disease continue to be effective, urgent attention is needed to address the challenge of heart failure.
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