Evidence map›Paper›PMID 28719396›Full record

ReviewClinical obstetrics and gynecology2017

Preclinical Models of Ovarian Cancer: Pathogenesis, Problems, and Implications for Prevention.

Anthony N Karnezis, Kathleen R Cho

Abstract readReview
In one paragraph

Review in Clinical obstetrics and gynecology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
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  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anthony N Karnezis*Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada †Department of Pathology, University of Michigan School of Medicine, Ann Arbor, Michigan.
Kathleen R Cho

Funding

Molecular Pathogenesis of Ovarian Endometrioid AdenocarcinomasR01CA094172 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHO, KATHLEEN R. · 2002 to 2011
$2.8M
Credentialing Ovarian Cancer Models in the Context of the Dualistic Pathway ParadigmR01CA196619 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHO, KATHLEEN R. · 2016 to 2018
$1.4M
NCI NIH HHS R01 CA094172NCI NIH HHS R01 CA196619
6 · The paper itself

Abstract

Preclinical models are relatively underutilized and underfunded resources for modeling the pathogenesis and prevention of ovarian cancers. Several reviews have detailed the numerous published models of ovarian cancer. In this review, we will provide an overview of experimental model systems, their strengths and limitations, and use selected models to illustrate how they can be used to address specific issues about ovarian cancer pathogenesis. We will then highlight some of the preclinical prevention studies performed to date and discuss experiments needed to address important unanswered questions about ovarian cancer prevention strategies.

Indexed as

AnimalsCarcinomaChemopreventionChickensDisease Models, AnimalFemaleHumansMiceOvarian NeoplasmsOvariectomyProphylactic Surgical ProceduresSalpingectomy

Identifiers

PMID28719396
PMCPMC5843373

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.