Evidence map›Paper›PMID 28719274›Full record

ArticleThe American journal of tropical medicine and hygiene2017

Risk Factors for Podoconiosis: Kamwenge District, Western Uganda, September 2015.

Christine Kihembo, Ben Masiira, William Z Lali, Gabriel K Matwale, Joseph K B Matovu, Frank Kaharuza, Alex R Ario, Immaculate Nabukenya, Issa Makumbi, Monica Musenero and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Global epidemiology of podoconiosis: A systematic review.PLoS neglected tropical diseases · 2018
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Podoconiosis in Uganda: prevalence, geographical distribution and risk factors.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Christine KihemboEpidemiology and Surveillance Division, Ministry of Health, Kampala, Uganda.
Ben MasiiraEpidemiology and Surveillance Division, Ministry of Health, Kampala, Uganda.
William Z LaliWorld Health Organization Uganda Country Office, Kampala, Uganda.
Gabriel K MatwaleVector Control Division, Ministry of Health, Kampala, Uganda.
Joseph K B MatovuMakerere University School of Public Health, Kampala, Uganda.
Frank KaharuzaMakerere University School of Public Health, Kampala, Uganda.
Alex R ArioUganda Public Health Fellowship Program, Field Epidemiology Track, Kampala, Uganda.
Immaculate NabukenyaEpidemiology and Surveillance Division, Ministry of Health, Kampala, Uganda.
Issa MakumbiPublic Health Emergency Operations Centre, Ministry of Health, Kampala, Uganda.
Monica MuseneroEpidemiology and Surveillance Division, Ministry of Health, Kampala, Uganda.
Bao-Ping ZhuU.S. Centers for Disease Control and Prevention, Kampala, Uganda.
Miriam NanyunjaWorld Health Organization Uganda Country Office, Kampala, Uganda.
Ministry of Health · UGMakerere University · UGCenters for Disease Control and Prevention · UG

Funding

World Health Organization 001
6 · The paper itself

Abstract

AbstractPodoconiosis, a noninfectious elephantiasis, is a disabling neglected tropical disease. In August 2015, an elephantiasis case-cluster was reported in Kamwenge District, western Uganda. We investigated to identify the disease's nature and risk factors. We defined a suspected podoconiosis case as onset in a Kamwenge resident of bilateral asymmetrical lower limb swelling lasting ≥ 1 month, plus ≥ 1 of the following associated symptoms: skin itching, burning sensation, plantar edema, lymph ooze, prominent skin markings, rigid toes, or mossy papillomata. A probable case was a suspected case with negative microfilaria antigen immunochromatographic card test (ruling out filarial elephantiasis). We conducted active case-finding. In a case-control investigation, we tested the hypothesis that the disease was caused by prolonged foot skin exposure to irritant soils, using 40 probable case-persons and 80 asymptomatic village control-persons, individually matched by age and sex. We collected soil samples to characterize irritants. We identified 52 suspected (including 40 probable) cases with onset from 1980 to 2015. Prevalence rates increased with age; annual incidence (by reported onset of disease) was stable over time at 2.9/100,000. We found that 93% (37/40) of cases and 68% (54/80) of controls never wore shoes at work (Mantel-Haenszel odds ratio [OR

Indexed as

AdolescentAdultAgedAged, 80 and overCase-Control StudiesElephantiasisElephantiasis, FilarialFemaleHealth BehaviorHumansHygieneMaleMiddle AgedNeglected DiseasesPrevalenceRisk FactorsSoil

Identifiers

PMID28719274
PMCPMC5462591
OpenAlexW2605791600

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.