ArticleAnnals of neurology2017
Multimodal image analysis of clinical influences on preterm brain development.
Article in Annals of neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Fetal brain MRI atlases and datasets: A review.NeuroImage · 2024Pooled it
- Trial
- The Earliest Impressions: A Systematic Review of Early-Life Exposures on Brain Structure and Neurodevelopmental Outcomes.bioRxiv : the preprint server for biology · 2026Article
- Associations between neonatal brain structure and neurodevelopmental outcomes following very preterm birth.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Prediction of motor developmental outcomes based on MRI radiomics in premature infants.Pediatric research · 2026Article
- Functional connectivity patterns as an early indicator of later very early preterm outcomes.Developmental cognitive neuroscience · 2026Article
- Wired from the womb: a narrative review of fetal and neonatal connectomics via fMRI and emerging neurotechnologies.Pediatric research · 2026Review
- Diffuse white matter abnormality is independently predictive of neurodevelopmental outcomes in preterm infants.Archives of disease in childhood. Fetal and neonatal edition · 2026Article
- Edge participation coefficient unveiling the developmental dynamics of neonatal functional connectome.Communications biology · 2025Article
- Early Development and Co-Evolution of Microstructural and Functional Brain Connectomes: A Multi-Modal MRI Study in Preterm and Full-Term Infants.Human brain mapping · 2025Article
- Article
- Neonatal brain MRI to prognosticate neurodevelopmental outcomes in fetal growth restricted infants: a systematic review.Frontiers in pediatrics · 2025Review
- A multimodal neural signature of face processing in autism within the fusiform gyrus.Nature. Mental health · 2025Article
- Socioeconomic status moderates associations between hippocampal development and cognition in preterms.Annals of clinical and translational neurology · 2024Article
- Multi-source multi-modal markers for Bayesian Networks: Application to the extremely preterm born brain.Medical image analysis · 2024Article
- Early biomarkers of neurodevelopmental disorders in preterm infants: protocol for a longitudinal cohort study.BMJ open · 2023Article
- Parsing brain-behavior heterogeneity in very preterm born children using integrated similarity networks.Translational psychiatry · 2023Article
- Diffuse excessive high signal intensity in the preterm brain on advanced MRI represents widespread neuropathology.NeuroImage · 2022Article
- Article
- Language function following preterm birth: prediction using machine learning.Pediatric research · 2022Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
objectivePremature birth is associated with numerous complex abnormalities of white and gray matter and a high incidence of long-term neurocognitive impairment. An integrated understanding of these abnormalities and their association with clinical events is lacking. The aim of this study was to identify specific patterns of abnormal cerebral development and their antenatal and postnatal antecedents.
methodsIn a prospective cohort of 449 infants (226 male), we performed a multivariate and data-driven analysis combining multiple imaging modalities. Using canonical correlation analysis, we sought separable multimodal imaging markers associated with specific clinical and environmental factors and correlated to neurodevelopmental outcome at 2 years.
resultsWe found five independent patterns of neuroanatomical variation that related to clinical factors including age, prematurity, sex, intrauterine complications, and postnatal adversity. We also confirmed the association between imaging markers of neuroanatomical abnormality and poor cognitive and motor outcomes at 2 years.
interpretationThis data-driven approach defined novel and clinically relevant imaging markers of cerebral maldevelopment, which offer new insights into the nature of preterm brain injury. Ann Neurol 2017;82:233-246.
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