ArticleNutrients2017
Dose-Dependent Prebiotic Effect of Lactulose in a Computer-Controlled In Vitro Model of the Human Large Intestine.
Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06995586 (The Synergistic Action of Vitamins and Dietary Supplements in Patients With Coronary Artery Bypass Grafting for Improving the Quality of Healthcare Delivery.), which is not on this map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Synergistic Action of Vitamins and Dietary Supplements in Patients With Coronary Artery Bypass Grafting for Improving the Quality of Healthcare Delivery.
Who cites it
28 citing papers in PubMed, 62 citations in OpenAlex.
- Effect of Bacillus coagulans Unique IS2 with Lactulose on Functional Constipation in Adults: a Double-Blind Placebo Controlled Study.Probiotics and antimicrobial proteins · 2023Trial
- Prevention of anastomotic leak in rectal cancer surgery with local antibiotic decontamination: a prospective, randomized, double-blind, placebo-controlled single center trial.International journal of colorectal disease · 2020Trial
- From Bioreactors to Organoids: Tools for Culturing and Understanding Microbiota.Indian journal of microbiology · 2025Review
- Application of Artificial Gastrointestinal Tract Models in Veterinary Medicine.Animals : an open access journal from MDPI · 2025Review
- Protective effect of low-dose lactulose in dextran sulfate sodium induced ulcerative colitis model of rats.Scientific reports · 2025Article
- Infection, inflammation and hepatic encephalopathy from a clinical perspective.Metabolic brain disease · 2024Review
- Development of an infant colon simulatingMicrobiology spectrum · 2024Article
- A synbiotic of Anaerostipes caccae and lactulose prevents and treats food allergy in mice.Cell host & microbe · 2024Article
- The Role of Prebiotics in Modulating Gut Microbiota: Implications for Human Health.International journal of molecular sciences · 2024Review
- The Bridge Between Ischemic Stroke and Gut Microbes: Short-Chain Fatty Acids.Cellular and molecular neurobiology · 2023Review
- Interventional strategies for ischemic stroke based on the modulation of the gut microbiota.Frontiers in neuroscience · 2023Review
- Co-Administration of Lactulose Crystals with Amoxicillin Followed by Prolonged Lactulose Treatment Promotes Recovery of the Human Gut Microbiome In Vitro.Antibiotics (Basel, Switzerland) · 2022Article
- Artificial Gastrointestinal Models for Nutraceuticals Research-Achievements and Challenges: A Practical Review.Nutrients · 2022Review
- Recent developments in microbial production of high-purity galacto-oligosaccharides.World journal of microbiology & biotechnology · 2022Review
- Lactulose Modulates the Structure of Gut Microbiota and Alleviates Colitis-Associated Tumorigenesis.Nutrients · 2022Article
- Butyrate producers, "The Sentinel of Gut": Their intestinal significance with and beyond butyrate, and prospective use as microbial therapeutics.Frontiers in microbiology · 2022Review
- Highlighting the Relevance of Gut Microbiota Manipulation in Inflammatory Bowel Disease.Diagnostics (Basel, Switzerland) · 2021Review
- Low-Dose Lactulose as a Prebiotic for Improved Gut Health and Enhanced Mineral Absorption.Frontiers in nutrition · 2021Review
- Lactulose Improves Neurological Outcomes by Repressing Harmful Bacteria and Regulating Inflammatory Reactions in Mice After Stroke.Frontiers in cellular and infection microbiology · 2021Article
- Microbiota reprogramming for treatment of alcohol-related liver disease.Translational research : the journal of laboratory and clinical medicine · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lactulose, a disaccharide of galactose and fructose, used as a laxative or ammonia-lowering drug and as a functional food ingredient, enhances growth of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.