Evidence map›Paper›PMID 28718821›Full record

ArticleInternational journal of molecular sciences2017

Tick Haller's Organ, a New Paradigm for Arthropod Olfaction: How Ticks Differ from Insects.

Ann L Carr, Robert D Mitchell, Anirudh Dhammi, Brooke W Bissinger, Daniel E Sonenshine, R Michael Roe

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 66 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. The BiteBarrier perimeter: A passive spatial device for tick control and bite prevention.Current research in parasitology & vector-borne diseases · 2025
    Article
  7. Article
  8. Risk ofPathogens (Basel, Switzerland) · 2024
    Article
  9. Article
  10. Insects · 2023
    Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ann L CarrDepartment of Entomology and Plant Pathology, North Carolina State University, Raleigh, NC 27695,USA. alcarr2@ncsu.edu.
Robert D MitchellDepartment of Entomology and Plant Pathology, North Carolina State University, Raleigh, NC 27695,USA. rdmitche@ncsu.edu.
Anirudh DhammiDepartment of Entomology and Plant Pathology, North Carolina State University, Raleigh, NC 27695,USA. adhammi@ncsu.edu.
Brooke W BissingerAgBiome, Research Triangle Park, NC 27709, USA. dsonensh@odu.edu.
Daniel E SonenshineDepartment of Biological Sciences, Old Dominion University, Norfolk, VA 23529, USA. dsonensh@odu.edu.
R Michael RoeDepartment of Entomology and Plant Pathology, North Carolina State University, Raleigh, NC 27695,USA. mroe@ncsu.edu.
North Carolina State University · USOld Dominion University · USResearch Triangle Park Foundation · US

Funding

First Transcriptome to the Tick Olfactory SystemR21AI096268 · NIAID · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI ROE, RICHARD MICHAEL · 2011 to 2012
$423k
NIAID NIH HHS R21 AI096268
6 · The paper itself

Abstract

Ticks are the vector of many human and animal diseases; and host detection is critical to this process. Ticks have a unique sensory structure located exclusively on the 1st pairs of legs; the fore-tarsal Haller's organ, not found in any other animals, presumed to function like the insect antennae in chemosensation but morphologically very different. The mechanism of tick chemoreception is unknown. Utilizing next-generation sequencing and comparative transcriptomics between the 1st and 4th legs (the latter without the Haller's organ), we characterized 1st leg specific and putative Haller's organ specific transcripts from adult American dog ticks,

Indexed as

SmellAmino Acid SequenceAnimalsAnimal StructuresBehavior, AnimalInsect ProteinsMalePhylogenyRNA, MessengerSensory Receptor CellsSequence Analysis, RNATasteTicksTranscriptomeInsect ProteinsRNA, MessengerAmerican dog tickchemoreceptionDEETDermacentor variabilisGPCRgustationHaller’s organodorant binding proteinsolfactionticktranscriptome

Identifiers

PMID28718821
PMCPMC5536051
OpenAlexW2739156894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.