Evidence map›Paper›PMID 28718799›Full record

ReviewInternational journal of molecular sciences2017

Zebrafish as a Model Organism for the Development of Drugs for Skin Cancer.

Fatemeh Bootorabi, Hamed Manouchehri, Reza Changizi, Harlan Barker, Elisabetta Palazzo, Annalisa Saltari, Mataleena Parikka, Carlo Pincelli, Ashok Aspatwar

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. The role of SPRED1 mutation in melanoma.European journal of medical research · 2025
    Review
  3. Emerging Frontiers in Zebrafish Embryonic and Adult-Derived Cell Lines.International journal of molecular sciences · 2025
    Review
  4. Review
  5. Article
  6. Zebrafish live imaging: a strong weapon in anticancer drug discovery and development.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Zebrafish and Flavonoids: Adjuvants against Obesity.Molecules (Basel, Switzerland) · 2021
    Review
  20. Kynurenic acid and cancer: facts and controversies.Cellular and molecular life sciences : CMLS · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fatemeh BootorabiBiosensor Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, 14114 Tehran, Iran. fatemeh.bootorabi@gmail.com.
Hamed ManouchehriDepartment of Aquaculture, Babol Branch, Islamic Azad University, 47134 Babol, Iran. hd_manuchehri@yahoo.com.
Reza ChangiziDepartment of Aquaculture, Babol Branch, Islamic Azad University, 47134 Babol, Iran. rech76ir@gmail.com.
Harlan BarkerFaculty of Medicine and Life Sciences, University of Tampere, 33014 Tampere, Finland. harlan.barker@uta.fi.
Elisabetta PalazzoLaboratory of Cutaneous Biology, Department of Surgical, Medical, Dental and Morphological Sciences, University of Modena and Reggio Emilia, 41100 Modena, Italy. elisabetta.palazzo1@gmail.com.
Annalisa SaltariLaboratory of Cutaneous Biology, Department of Surgical, Medical, Dental and Morphological Sciences, University of Modena and Reggio Emilia, 41100 Modena, Italy. annalisax85@alice.it.
Mataleena ParikkaFaculty of Medicine and Life Sciences, University of Tampere, Oral and Maxillofacial Unit, Tampere University Hospital, 33014 Tampere, Finland. mataleena.parikka@uta.fi.
Carlo PincelliLaboratory of Cutaneous Biology, Department of Surgical, Medical, Dental and Morphological Sciences, University of Modena and Reggio Emilia, 41100 Modena, Italy. carlo.pincelli@unimore.it.
Ashok AspatwarFaculty of Medicine and Life Sciences, University of Tampere, 33014 Tampere, Finland. ashok.aspatwar@staff.uta.fi.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin cancer, which includes melanoma and squamous cell carcinoma, represents the most common type of cutaneous malignancy worldwide, and its incidence is expected to rise in the near future. This condition derives from acquired genetic dysregulation of signaling pathways involved in the proliferation and apoptosis of skin cells. The development of animal models has allowed a better understanding of these pathomechanisms, with the possibility of carrying out toxicological screening and drug development. In particular, the zebrafish (

Indexed as

AnimalsAntineoplastic AgentsDisease Models, AnimalDrug DiscoveryHumansSkin NeoplasmsZebrafishAntineoplastic Agentsdrug developmentinhibitor screeningmelanomaskin cancersquamous cell carcinomatransgenic zebrafish

Identifiers

PMID28718799
PMCPMC5536038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.