Evidence map›Paper›PMID 28718507›Full record

ArticleThe Journal of physiology2017

Gene expression analyses reveal metabolic specifications in acute O

Lin Gao, Victoria Bonilla-Henao, Paula García-Flores, Ignacio Arias-Mayenco, Patricia Ortega-Sáenz, José López-Barneo

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 65 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Hif-2α programs oxygen chemosensitivity in chromaffin cells.The Journal of clinical investigation · 2024
    Article
  5. Hif1α-dependent mitochondrial acute ONature communications · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. The Adult Carotid Body: A Germinal Niche at the Service of Physiology.Advances in experimental medicine and biology · 2023
    Article
  10. Constitutive Expression of Hif2α Confers Acute OAdvances in experimental medicine and biology · 2023
    Article
  11. Transcriptomics of the Carotid Body.Advances in experimental medicine and biology · 2023
    Review
  12. Oxygen regulation of breathing is abolished in mitochondrial complex III-deficient arterial chemoreceptors.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lin GaoInstituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Spain.
Victoria Bonilla-HenaoInstituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Spain.
Paula García-FloresInstituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Spain.
Ignacio Arias-MayencoInstituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Spain.
Patricia Ortega-SáenzInstituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Spain.
José López-BarneoInstituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Spain.ORCID 0000-0003-4101-6095
Biomedical Research Networking Center on Neurodegenerative Diseases · ES

Funding

NINDS NIH HHS N01 NS002331
6 · The paper itself

Abstract

key pointsGlomus cells in the carotid body (CB) and chromaffin cells in the adrenal medulla (AM) are essential for reflex cardiorespiratory adaptation to hypoxia. However, the mechanisms whereby these cells detect changes in O ABSTRACT: Acute O

Indexed as

TranscriptomeAnimalsBasic Helix-Loop-Helix ProteinsCarotid BodyCells, CulturedChemoreceptor CellsEndothelial PAS Domain-Containing Protein 1FemaleHypoxiaIsocitrate DehydrogenaseMaleMiceMice, Inbred C57BLOxygenPotassium ChannelsProcollagen-Proline DioxygenaseBasic Helix-Loop-Helix ProteinsEndothelial PAS Domain-Containing Protein 1Isocitrate DehydrogenaseOxygenPHD3 protein, mousePotassium ChannelsProcollagen-Proline Dioxygenaseacute oxygen sensingcarotid bodygene expressionperipheral chemoreceptors

Identifiers

PMID28718507
PMCPMC5599487
OpenAlexW2735380392

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.