Evidence map›Paper›PMID 28718502›Full record

ReviewFEBS letters2017

Chansporter complexes in cell signaling.

Geoffrey W Abbott

Open access · bronzeAbstract readReview
In one paragraph

Review in FEBS letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Chloride Gradient Is Involved in Ammonium Influx in Human Erythrocytes.International journal of molecular sciences · 2024
    Article
  3. Review
  4. Article
  5. Article
  6. Frontiers in cell and developmental biology · 2020
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Geoffrey W AbbottBioelectricity Laboratory, Department of Physiology and Biophysics, School of Medicine, University of California, Irvine, CA, USA.
University of California, Irvine · US

Funding

THYROID SODIUM I/ SYMPORTERR01DK041544 · NIDDK · YESHIVA UNIVERSITY · PI ABBOTT, GEOFFREY W, CARRASCO, NANCY · 1989 to 2017
$5.6M
Ion channel-transporter interactionsR01GM115189 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI ABBOTT, GEOFFREY W · 2015 to 2018
$1.1M
Real-time potassium channel subunit dynamicsR21DC015736 · NIDCD · UNIVERSITY OF CALIFORNIA-IRVINE · PI ABBOTT, GEOFFREY W · 2016 to 2017
$425k
Discovering the function of a putative ion channel family linked to inherited diseasesR21DC015982 · NIDCD · UNIVERSITY OF CALIFORNIA-IRVINE · PI ABBOTT, GEOFFREY W · 2017 to 2018
$425k
NIDCD NIH HHS R21 DC015736NIDCD NIH HHS R21 DC015982NIDDK NIH HHS R01 DK041544NIGMS NIH HHS R01 GM115189
6 · The paper itself

Abstract

Ion channels facilitate diffusion of ions across cell membranes for such diverse purposes as neuronal signaling, muscular contraction, and fluid homeostasis. Solute transporters often utilize ionic gradients to move aqueous solutes up their concentration gradient, also fulfilling a wide variety of tasks. Recently, an increasing number of ion channel-transporter ('chansporter') complexes have been discovered. Chansporter complex formation may overcome what could otherwise be considerable spatial barriers to rapid signal integration and feedback between channels and transporters, the ions and other substrates they transport, and environmental factors to which they must respond. Here, current knowledge in this field is summarized, covering both heterologous expression structure/function findings and potential mechanisms by which chansporter complexes fulfill contrasting roles in cell signaling in vivo.

Indexed as

Signal TransductionAnimalsCell MembraneHumansIon ChannelsIon Channelsion channelmyo-inositolsolute transporter

Identifiers

PMID28718502
PMCPMC5678956
OpenAlexW2736702949

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.