ArticleCNS oncology2017
Modern approaches to the management of metastatic epidural spinal cord compression.
Article in CNS oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Incidence, epidemiology, radiology, and classification of metastatic spine tumors: WFNS Spine Committee recommendations.Neurosurgical review · 2024Pooled it
- Does Duration of Symptoms in Metastatic Spine Disease Affect Recovery and Outcomes? A Systematic Review and Meta-Analysis.Global spine journal · 2026Review
- Spine surgery for metastatic spine cancer in the era of advanced radiation therapy.Asian spine journal · 2026Article
- Using Time-Staged Palliative Conventional Radiation Therapy Followed by Stereotactic Body Radiation Therapy in Malignant Epidural Extension for a Nonsurgical Candidate.Advances in radiation oncology · 2025Article
- Microscopically-assisted Uninstrumented Surgical Tumor Decompression as an alternative to open surgery for symptomatic metastatic epidural spinal cord compression.Journal of spine surgery (Hong Kong) · 2025Article
- Favorable neurological recovery for MESCC-induced paralysis with median 9-day duration before surgery.Journal of orthopaedic surgery and research · 2024Article
- Review
- Review
- Separation surgery for metastatic epidural spinal cord compression: A qualitative review.Journal of bone oncology · 2020Review
- Metastatic epidural spinal cord compression.Journal of surgical case reports · 2020Article
- Metastatic Melanoma Epidural Tumour Regression Following Percutaneous Radiofrequency Ablation.Cureus · 2020Article
- Evaluate the characteristics and clinical significance of "toxic twin-leaf" sign in spinal epidural metastases before percutaneous vertebroplasty.Journal of interventional medicine · 2020Article
- Clinical results of carbon-ion radiotherapy with separation surgery for primary spine/paraspinal sarcomas.International journal of clinical oncology · 2019Article
- Decision Making in Patients With Metastatic Spine. The Role of Minimally Invasive Treatment Modalities.Frontiers in oncology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metastatic epidural spinal cord compression (MESCC) is an oncologic emergency requiring prompt treatment to maximize neurologic function, ambulatory function and local control. Traditionally, options for MESCC included external beam radiation therapy with or without surgery. Surgery has usually been reserved for the patient with optimal performance status, single level MESCC or mechanical instability. Advances in external beam radiation therapy such as the development of stereotactic body radiation therapy have allowed for the delivery of high-dose radiation, allowing for both long-term pain and local control. Surgical advances, such as separation surgery, minimal access spine surgery and percutaneous instrumentation, have decreased surgical morbidity. This review summarizes the latest advances and evidence in MESCC to enable modern management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.