ArticleCanadian journal of anaesthesia = Journal canadien d'anesthesie2017
Risk factors for delirium after cardiac surgery: a historical cohort study outlining the influence of cardiopulmonary bypass.
Article in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02548975 (Risk Factors for Delirium Following Cardiac Surgery), which is not on this map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Risk Factors for Delirium Following Cardiac Surgery
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- Association Between Perioperative Sleep Disorders and Post-Operative Delirium in Cardiac Surgeries: A Systematic Review and Meta-Analysis.Journal of sleep research · 2026Pooled it
- The Effects of Dexmedetomidine on Postoperative Delirium in Adult Cardiac Surgical Patients: A Bayesian Meta-Analysis and Trial Sequential Analysis.Acta anaesthesiologica Scandinavica · 2025Pooled it
- Effect of mannitol on postoperative delirium in patients undergoing coronary artery bypass graft: a randomised controlled trial.Open heart · 2024Trial
- Ramelteon for Prevention of Postoperative Delirium: A Randomized Controlled Trial in Patients Undergoing Elective Pulmonary Thromboendarterectomy.Critical care medicine · 2019Trial
- Comparison of postoperative delirium within 24 hours between ketamine and propofol infusion during cardiopulmonary bypass machine: A randomized controlled trial.Annals of cardiac anaesthesiaTrial
- Validation of intraoperative processed electroencephalography and cerebral oximetry for prediction of postoperative delirium in cardiac surgery: a prospective observational study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2026Observational
- Association between EuroSCORE II and postoperative delirium in cardiac surgery patients: a prospective cross-sectional study.Annals of medicine and surgery (2012) · 2025Article
- Predicting Postoperative Delirium in Older Patients Before Elective Surgery: Multicenter Retrospective Cohort Study.JMIR aging · 2025Article
- Hemodynamic control during cardiopulmonary bypass and the incidence of postoperative delirium- a post hoc analysis.BMC anesthesiology · 2025Article
- Evaluation of postoperative delirium in cardiac surgery patients with the SDACS screening tool: a multicenter-multiphase study.Perioperative medicine (London, England) · 2025Article
- Analysis of Risk Factors and Development of a Predictive Model for Delirium in ICU Patients: Construction, Validation, and Clinical Implications.International journal of general medicine · 2025Article
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- Post-cardiac Surgery Delirium: When the Details Matter!Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- Postoperative cognitive dysfunction in elderly postcardiac surgery patients: progress in rehabilitation application research.Frontiers in rehabilitation sciences · 2024Review
- Temperature management in acute type A aortic dissection treatment: deep vs. moderate hypothermic circulatory arrest. Is colder better?Frontiers in cardiovascular medicine · 2024Article
- Serum NPTX2 as a Potential Predictive Biomarker for Postoperative Delirium in Patients with Acute Type A Aortic Dissection.Neuropsychiatric disease and treatment · 2024Article
- Effects of Postoperative Blood Pressure Management on Delirium Among Patients in the Intensive Care Unit After Cardiac Surgery: An Observational Cohort Study.Journal of cardiothoracic and vascular anesthesia · 2023Observational
- Intraoperative plasma proteomic changes in cardiac surgery: In search of biomarkers of post-operative delirium.Proteomics. Clinical applications · 2023Article
- Postoperative delirium: identifying the patient at risk and altering the course: A narrative review.European journal of anaesthesiology and intensive care · 2023Review
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
purposeCardiopulmonary bypass (CPB) induces a significant inflammatory response that may increase the risk for delirium. We hypothesized that exposure to CPB during coronary artery bypass grafting (CABG) surgery would correlate with an increased risk of delirium.
methodsWe reviewed clinical data from two databases at our medical centre - the Cardiac Surgery Perioperative Outcomes Database and the Society of Thoracic Surgeons Database. Patients undergoing elective CABG surgery (on-pump and off-pump) from November 1, 2009 to September 30, 2015 were included in the study. Delirium was defined as any postoperative positive Confusion Assessment Method for the Intensive Care Unit exam during the intensive care unit stay. We performed logistic regression to isolate the association between CPB exposure and delirium adjusted for predetermined risk factors and potential confounders.
resultsDuring the study period, 2,280 patients underwent elective CABG surgery, with 384 patients (16.9%) exposed to CPB. Delirium was diagnosed in 451 patients (19.8%). Exposure to CPB showed a significant independent association with delirium. Patients exposed to CPB for 142 min (90
conclusionsThe use and duration of cardiopulmonary bypass were associated with an increased risk of delirium in patients undergoing CABG surgery.
trial registrationwww.clinicaltrials.gov , NCT02548975. Registered 4 September 2015.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.