Evidence map›Paper›PMID 28718047›Full record

ArticleVirus genes2017

Antigenic variability of foot-and-mouth disease virus serotype O during serial cytolytic passage.

Saravanan Subramaniam, Biswajit Das, Jitendra K Biswal, Rajeev Ranjan, Bramhadev Pattnaik

Abstract read
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In one paragraph

Article in Virus genes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Saravanan SubramaniamICAR-Directorate on Foot-and-Mouth Disease, Mukteswar-Kumaon, Nainital, 263138, India. saranvirol@gmail.com.
Biswajit DasICAR-Directorate on Foot-and-Mouth Disease, Mukteswar-Kumaon, Nainital, 263138, India.
Jitendra K BiswalICAR-Directorate on Foot-and-Mouth Disease, Mukteswar-Kumaon, Nainital, 263138, India.
Rajeev RanjanICAR-Directorate on Foot-and-Mouth Disease, Mukteswar-Kumaon, Nainital, 263138, India.
Bramhadev PattnaikICAR-Directorate on Foot-and-Mouth Disease, Mukteswar-Kumaon, Nainital, 263138, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence and disappearance of antigenic variants of foot-and-mouth disease virus (FMDV) during a field outbreak occurs periodically due to the volatile nature of its genome. In the present analysis, change in antigenic behavior of serotype O FMDV during the serial cytolytic passage in the absence of immune pressure was observed. Initially, the isolate showed a poor antigenic match (relationship value <0.3) with the serotype O vaccine strain and upon serial passage increase in relationship value was observed. Comparison of capsid sequence revealed substitution at four positions (VP3:K

Indexed as

Amino Acid SubstitutionAnimalsAntigenic VariationAntigens, ViralCapsid ProteinsFoot-and-Mouth DiseaseFoot-and-Mouth Disease VirusSerial PassageSerogroupAntigens, ViralCapsid ProteinsAntigenic variabilityCytolytic passageFMDVSerotype OSite IV

Identifiers

PMID28718047

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.