Evidence map›Paper›PMID 28717911›Full record

ArticleWorld journal of surgery2017

Laparoscopic Compared to Open Repeat Hepatectomy for Colorectal Liver Metastases: a Multi-institutional Propensity-Matched Analysis of Short- and Long-Term Outcomes.

Julie Hallet, Antonio Sa Cunha, Daniel Cherqui, Brice Gayet, Diane Goéré, Philippe Bachellier, Alexis Laurent, David Fuks, Francis Navarro, Patrick Pessaux and 1 more

Registry-linked trialAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in World journal of surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04163887 (Effect of the Laparoscopic Approach in Reducing Postoperative Severe Complications Following Hepatectomy for Colorectal Liver Metastases), which is not on this map. Cited by 30 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 6 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04163887 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Effect of the Laparoscopic Approach in Reducing Postoperative Severe Complications Following Hepatectomy for Colorectal Liver Metastases: Prospective, Randomized, Controlled Study

TypeinterventionalSponsorInstitut Mutualiste MontsourisRan2021 to 2026Enrolled340ConditionsLiver Metastasis Colon Cancer, Postoperative ComplicationsArmshepatectomy
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 6 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
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  5. [Evidence of minimally invasive oncological surgery of the liver].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021
    Pooled it
  6. Pooled it
  7. Trial
  8. Article
  9. Advantages of the Laparoscopic Approach for the Initial Operation in Patients who Underwent Repeat Hepatectomy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. LaparoscopicWorld journal of gastrointestinal surgery · 2022
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 10 institutions in 2 countries.

Julie HalletInstitut Hospitalo-Universitaire (IHU), Institute for Minimally Hybrid Invasive Image-Guided Surgery, Université de Strasbourg, Strasbourg, France.
Antonio Sa CunhaDepartment of Surgery, Hôpital Paul Brousse, Villejuif, France.
Daniel CherquiDepartment of Surgery, Hôpital Paul Brousse, Villejuif, France.
Brice GayetDepartment of Surgery, Institut Mutualiste Montsouris, Paris, France.
Diane GoéréDepartment of Sugery, Institut Gustave Roussy, Villejuif, France.
Philippe BachellierDepartment of Surgery, Hôpital Hautepierre, Strasbourg, France.
Alexis LaurentDepartment of Surgery, Hôpital Henri-Mondor, Créteil, France.
David FuksDepartment of Surgery, Institut Mutualiste Montsouris, Paris, France.
Francis NavarroDepartment of Surgery, Hôpital Saint-Éloi, Montpellier, France.
Patrick PessauxInstitut Hospitalo-Universitaire (IHU), Institute for Minimally Hybrid Invasive Image-Guided Surgery, Université de Strasbourg, Strasbourg, France. patrick.pessaux@chru-strasbourg.fr.
French Colorectal Liver Metastases Working Group, Association Française de Chirurgie
Hôpital Paul-Brousse · FRHôpital d'Hautepierre · FRInstitute Mutualiste Montsouris · FRHôpital Saint Eloi · FRHôpitaux Universitaires Henri-Mondor · FRInstitut de Chirurgie Guidée par l'Image · FRInstitut Gustave Roussy · FRUniversité de Strasbourg · FRInstitut de Recherche contre les Cancers de l’Appareil Digestif · FRSunnybrook Health Science Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWhile uptake of laparoscopic hepatectomy has improved, evidence on laparoscopic re-hepatectomy (LRH) for colorectal liver metastases (CRLMs) is limited and has never been compared to the open approach. We sought to define outcomes of LRH compared to open re-hepatectomy (ORH).

methodsPatients undergoing re-hepatectomy for CRLM at 39 institutions (2006-2013) were identified. Primary outcomes were 30-day post-operative overall morbidity, mortality, and length of stay. Secondary outcomes were recurrence and survival at latest follow-up. LRHs were matched to ORHs (1:3) using a propensity score created by comparing pre-operative clinicopathologic factors (number and size of liver metastases and major hepatectomy).

resultsOf 376 re-hepatectomies included, 27 were LRH, including 1 (3.7%) conversion. The propensity-matched cohort included 108 patients. Neither median operative time (252 vs. 230 min; p = 0.82) nor overall 30-day morbidity (48.1 vs. 38.3%; p = 0.37) differed. Non-specific morbidity (including cardiac, respiratory, infectious, and renal events) decreased with LRH (11.1 vs. 30.9%, p = 0.04), while surgical-specific morbidity, including liver insufficiency, was higher (44.4 vs. 22.2%, p = 0.03). One ORH and 0 LRH suffered 30-day mortality. Median length of stay (9 vs. 12 days; p = 0.60) was comparable. At latest follow-up, 26 (96.3%) LRH and 67 (82.7%) ORH patients were alive. Eight (29.6%) LRH and 36 (44.4%) ORH patients were alive without disease.

conclusionLRH for recurrent CRLM was associated with overall short-term outcomes comparable to ORH, but different morbidity profiles. While it may offer a safe and feasible approach, further insight is necessary to better define patient selection.

Indexed as

AgedColorectal NeoplasmsFemaleHepatectomyHumansLaparoscopyLength of StayLiver NeoplasmsMaleMiddle AgedOperative TimePostoperative ComplicationsPropensity ScoreReoperationRetrospective StudiesSurvival Rate

Identifiers

PMID28717911
OpenAlexW2734720250

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.