Evidence map›Paper›PMID 28717819›Full record

ArticleExperimental brain research2017

Atrophic degeneration of cerebellum impairs both the reactive and the proactive control of movement in the stop signal paradigm.

Giusy Olivito, Emiliano Brunamonti, Silvia Clausi, Pierpaolo Pani, Francesca R Chiricozzi, Margherita Giamundo, Marco Molinari, Maria Leggio, Stefano Ferraina

Abstract read
PubMed Publisher
In one paragraph

Article in Experimental brain research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Neuronal Activity in the Premotor Cortex of Monkeys Reflects Both Cue Salience and Motivation for Action Generation and Inhibition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  7. Article
  8. Action Control Deficits in Patients With Essential Tremor.Journal of the International Neuropsychological Society : JINS · 2019
    Article
  9. The Implementation of Predictions During Sequencing.Frontiers in cellular neuroscience · 2019
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Giusy OlivitoAtaxia Research Lab, IRCCS Santa Lucia Foundation, Rome, Italy.
Emiliano BrunamontiDepartment of Physiology and Pharmacology, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.
Silvia ClausiAtaxia Research Lab, IRCCS Santa Lucia Foundation, Rome, Italy.
Pierpaolo PaniDepartment of Physiology and Pharmacology, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.
Francesca R ChiricozziAtaxia Research Lab, IRCCS Santa Lucia Foundation, Rome, Italy.
Margherita GiamundoDepartment of Physiology and Pharmacology, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.
Marco MolinariRobotic Neurorehabilitation Lab, Neurorehabilitation 1 and Spinal Center, IRCCS Santa Lucia Foundation, Rome, Italy.
Maria LeggioAtaxia Research Lab, IRCCS Santa Lucia Foundation, Rome, Italy. maria.leggio@uniroma1.it.
Stefano FerrainaDepartment of Physiology and Pharmacology, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy. stefano.ferraina@uniroma1.it.
Sapienza University of Rome · ITFondazione Santa Lucia · IT

Funding

Ministero della Salute GR-2013-02354888Ministero della Salute (IT) RF-2011-02348213
6 · The paper itself

Abstract

The cognitive control of movement suppression, including performance monitoring, is one of the core properties of the executive system. A complex cortical and subcortical network involving cerebral cortex, thalamus, subthalamus, and basal ganglia has been regarded as the neural substrate of inhibition of programmed movements. Using the countermanding task, a suitable tool to explore behavioral components of movement suppression, the contribution of the cerebellum in the proactive control and monitoring of voluntary action has been recently described in patients affected by focal lesions involving in particular the cerebellar dentate nucleus. Here, we evaluated the performance on the countermanding task in a group of patients with cerebellar degeneration, in which the cerebellar cortex was diffusely affected, and showed that they display additionally a longer latency in countermanding engaged movements. Overall, the present data confirm the role of the cerebellum in executive control of action inhibition by extending the contribution to reactive motor suppression.

Indexed as

Inhibition, PsychologicalAdultAtrophyCerebellar CortexExecutive FunctionFemaleFriedreich AtaxiaHumansMaleMiddle AgedMotor ActivityPsychomotor PerformanceSpinocerebellar AtaxiasBasal gangliaCortical cerebellar degenerationInhibitionMovement generationStop signal reaction time

Identifiers

PMID28717819
OpenAlexW2736198619

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.