Evidence map›Paper›PMID 28717616›Full record

ArticleMuscles, ligaments and tendons journal

Topical polidocanol application in combination with static stretching in tendinopathies: a prospective pilot study.

Matthias Gatz, Simone Schrading, Timm Dirrichs, Marcel Betsch, Markus Tingart, Björn Rath, Christiane Kuhl, Valentin Quack

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Muscles, ligaments and tendons journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Matthias GatzDepartment of Orthopaedics, RWTH Aachen, Germany.
Simone SchradingDepartment of Diagnostic and Interventional Radiology, RWTH Aachen University Hospital, Germany.
Timm DirrichsDepartment of Diagnostic and Interventional Radiology, RWTH Aachen University Hospital, Germany.
Marcel BetschDepartment of Orthopaedics, RWTH Aachen, Germany.
Markus TingartDepartment of Orthopaedics, RWTH Aachen, Germany.
Björn RathDepartment of Orthopaedics, RWTH Aachen, Germany.
Christiane KuhlDepartment of Diagnostic and Interventional Radiology, RWTH Aachen University Hospital, Germany.
Valentin QuackDepartment of Orthopaedics, RWTH Aachen, Germany.
RWTH Aachen University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHighly operator-based injection therapy with vasosclerosing and anesthetic polidocanol is used for tendinopathies. This pilot-study evaluates the topical application of polidocanol gel.

methodsProspective case series. 39 patients with tendinopathies (14 Achilles, 14 patella, 11 wrist extensors) with a symptom duration > 6 months were included. Polidocanol and static stretching were the therapy in the first 2 weeks, while static stretching was continuously performed for 6 months. Clinical outcome was evaluated with VISA-A, VISA-P and DASH Scores and sonographically with B-Mode (B-Mode), Power Doppler (PD) and Shearwave Elastography (SWE).

results22 patients clinically improved (>+10 score points), 11 patients were without improvement (<+ 10) and 1 patient worsened during 6 months. The VISA-A Score increased in average 19 points from 56 to 75 (p< 0.01), VISA-P Score increased 13 points from 59 to 72 (p< 0,01) and the DASH-Score decreased 20 points from 40 to 20 (p< 0,01). SWE correlates better than B-Mode or PD with symptom improvement.

conclusionThe combination of static training and topical polidocanol application seems to be successful in the treatment of tendinopathies. Further RCT studies need to evaluate the efficiency of topical polidocanol application. SWE is a more sensitive tool to describe symptom development than PD or B-Mode. LEVEL OF EVIDENCE: IV.

Indexed as

Achillesepicondylitispatellashear wave elastographytendinopathyultrasound

Identifiers

PMID28717616
PMCPMC5505600
OpenAlexW2734365469

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.