ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2017
Diagnostic value of alarm symptoms for upper GI malignancy in patients referred to GI clinic: A 7 years cross sectional study.
Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Yield of alarm features in predicting significant endoscopic findings among hospitalized patients with dyspepsia.World journal of gastroenterology · 2024Article
- The Swedish Standardized Course of Care-Diagnostic Efficacy in Esophageal and Gastric Cancer.Diagnostics (Basel, Switzerland) · 2023Article
- Dyspepsia with alarm symptoms in patients aged less than 60 years: Is upper gastrointestinal endoscopy justified in Indian scenario?Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2022Observational
- Serum pepsinogen level as a biomarker for atrophy, reflux esophagitis, and gastric cancer screening in Indonesia.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2022Article
- Use of alarm features in predicting significant endoscopic findings in Nigerian patients with dyspepsia.The Pan African medical journal · 2019Article
- Diagnosis of GERD in typical and atypical manifestations.Acta bio-medica : Atenei Parmensis · 2018Review
- A Simple Pre-endoscopy Score for Predicting Risk of Malignancy in Patients with Dyspepsia: A 5-Year Prospective Study.Digestive diseases and sciences · 2018Article
- Cancer trends in a province of Southwest of Iran, 2003-2016.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2018Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEarly upper gastrointestinal (UGI) cancer detection had led to organ-preserving endoscopic therapy. Endoscopy is a suitable method of early diagnosis of UGI malignancies. In Iran, exclusion of malignancy is the most important indication for endoscopy. This study is designed to see whether using alarm symptoms can predict the risk of cancer in patients. MATERIALS AND
methodsA total of 3414 patients referred to a tertiary gastrointestinal (GI) clinic in Isfahan, Iran, from 2009 to 2016 with dyspepsia, gastroesophageal reflux disease (GERD), and alarm symptoms, such as weight loss, dysphagia, GI bleeding, vomiting, positive familial history for cancer, and anorexia. Each patient had been underwent UGI endoscopy and patient data, including histology results, had been collected in the computer. We used logistic regression models to estimate the diagnostic accuracy of each alarm symptoms.
resultsA total of 3414 patients with alarm symptoms entered in this study, of whom 72 (2.1%) had an UGI malignancy. According to the logistic regression model, dysphagia (
conclusionWe recommend to do an early endoscopy for any patient with UGI symptoms and to take multiple biopsies from any rudeness or suspicious lesion, especially for male gender older than 50, dysphagia, or weight loss.
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