ArticleScientific reports2017
The molecular mechanisms of Monascus purpureus M9 responses to blue light based on the transcriptome analysis.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed.
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- Study on the effect of ascorbic acid on the biosynthesis of pigment and citrinin in red yeast rice based on comparative transcriptomics.Frontiers in microbiology · 2024Article
- Enhancing Eritadenine Production in Submerged Cultures of Shiitake (Mycobiology · 2024Article
- Mannitol improvesFrontiers in microbiology · 2023Article
- Production of Fungal Pigments: Molecular Processes and Their Applications.Journal of fungi (Basel, Switzerland) · 2022Review
- Comparative Transcriptomic and Metabolomic Analyses Reveal the Regulatory Effect and Mechanism of Tea Extracts on the Biosynthesis ofFoods (Basel, Switzerland) · 2022Article
- Comparative transcriptomics discloses the regulatory impact of carbon/nitrogen fermentation on the biosynthesis ofFood chemistry: X · 2022Article
- Diverse Effects of Amino Acids onFrontiers in microbiology · 2022Article
- Methionine and S-Adenosylmethionine RegulateFrontiers in microbiology · 2022Article
- Integrative Metabolomic and Transcriptomic Analyses Uncover Metabolic Alterations and Pigment Diversity inmSystems · 2021Article
- Comparative metabolomics analysis reveals the metabolic regulation mechanism of yellow pigment overproduction by Monascus using ammonium chloride as a nitrogen source.Applied microbiology and biotechnology · 2021Article
- Effect of Static Magnetic Field onJournal of fungi (Basel, Switzerland) · 2021Article
- Comparative transcriptomic analysis reveals the regulatory effects of inorganic nitrogen on the biosynthesis ofRSC advances · 2020Article
- Article
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6 authors.
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Abstract
Light is an important environmental factor that regulates various physiological processes of fungi. To thoroughly study the responses of Monascus to blue light, transcriptome sequencing was performed on mRNAs isolated from samples of Monascus purpureus M9 cultured under three conditions: darkness (D); exposure to blue light for 15 min/d (B15); and exposure to blue light for 60 min/d over 8 days (B60). The number of differentially expressed genes between the three pairs of samples-B15 vs D, B60 vs B15, and B60 vs D-was 1167, 1172, and 220, respectively. KEGG analysis showed the genes involved in primary metabolism including carbon and nitrogen metabolism were downregulated by B15 light treatment, whereas B15 upregulated expression of genes involved with aromatic amino acid metabolism, which associated with development, and branched chain amino acid metabolism, and fatty acid degradation, which can produce the biosynthetic precursors of pigments. When exposed to B60 conditions, genes with roles in carbohydrate metabolism and protein synthesis were upregulated as part of a stress response to blue light. Based on this study, we propose a predicted light-stimulated signal transduction pathway in Monascus. Our work is the first comprehensive investigation concerning the mechanism of Monascus responses to blue light.
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