Evidence map›Paper›PMID 28717248›Full record

ArticleScientific reports2017

Loss of type 9 adenylyl cyclase triggers reduced phosphorylation of Hsp20 and diastolic dysfunction.

Yong Li, Tanya A Baldwin, Yan Wang, Janani Subramaniam, Anibal Garza Carbajal, Cameron S Brand, Shane R Cunha, Carmen W Dessauer

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Compartmentalized cAMP signalling and control of cardiac rhythm.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  4. Article
  5. Preferential Expression of CaBiomolecules · 2022
    Article
  6. Review
  7. Expression and functions of adenylyl cyclases in the CNS.Fluids and barriers of the CNS · 2022
    Review
  8. Article
  9. Review
  10. Article
  11. Protein Composition and Biomedical Potential of the Skin Secretion ofInternational journal of peptide research and therapeutics · 2021
    Article
  12. Cross-Talk Between the Adenylyl Cyclase/cAMP Pathway and CaReviews of physiology, biochemistry and pharmacology · 2021
    Review
  13. Nanometric targeting of type 9 adenylyl cyclase in heart.Biochemical Society transactions · 2019
    Review
  14. Regulation of ICells · 2019
    Article
  15. Review
  16. Article
  17. Function of Adenylyl Cyclase in Heart: the AKAP Connection.Journal of cardiovascular development and disease · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yong LiDept. Integrative Biology and Pharmacology, McGovern Medical School, University of Texas Health Science Center, Houston, TX, 77030, USA.
Tanya A BaldwinDept. Integrative Biology and Pharmacology, McGovern Medical School, University of Texas Health Science Center, Houston, TX, 77030, USA.
Yan WangDept. Integrative Biology and Pharmacology, McGovern Medical School, University of Texas Health Science Center, Houston, TX, 77030, USA.
Janani SubramaniamDept. Integrative Biology and Pharmacology, McGovern Medical School, University of Texas Health Science Center, Houston, TX, 77030, USA.
Anibal Garza CarbajalDept. Integrative Biology and Pharmacology, McGovern Medical School, University of Texas Health Science Center, Houston, TX, 77030, USA.
Cameron S BrandDept. Integrative Biology and Pharmacology, McGovern Medical School, University of Texas Health Science Center, Houston, TX, 77030, USA.
Shane R CunhaDept. Integrative Biology and Pharmacology, McGovern Medical School, University of Texas Health Science Center, Houston, TX, 77030, USA.
Carmen W DessauerDept. Integrative Biology and Pharmacology, McGovern Medical School, University of Texas Health Science Center, Houston, TX, 77030, USA. Carmen.W.Dessauer@uth.tmc.edu.ORCID 0000-0003-1210-4280
The University of Texas Health Science Center at Houston · USThe University of Texas Health Science Center · USUniversity of California San Diego · US

Funding

REGULATION OF ADENYLYL CYCLASE SIGNALING PATHWAYSR01GM060419 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI DESSAUER, CARMEN W. · 2000 to 2021
$6.9M
Training in Pharmacological SciencesT32GM089657 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI HANCOCK, JOHN F · 2010 to 2014
$728k
NIGMS NIH HHS R01 GM060419NIGMS NIH HHS T32 GM089657
6 · The paper itself

Abstract

Adenylyl cyclase type 9 (AC9) is found tightly associated with the scaffolding protein Yotiao and the I

Indexed as

Adenylyl CyclasesA Kinase Anchor ProteinsAnimalsBradycardiaCyclic AMPCyclic AMP-Dependent Protein KinasesEchocardiographyFemaleHSP20 Heat-Shock ProteinsIsoproterenolKCNQ1 Potassium ChannelMaleMiceMice, Inbred C57BLMice, KnockoutMyocardiumadenylate cyclase 9Adenylyl CyclasesA Kinase Anchor ProteinsCyclic AMPCyclic AMP-Dependent Protein KinasesHSP20 Heat-Shock ProteinsIsoproterenolKCNQ1 Potassium Channel

Identifiers

PMID28717248
PMCPMC5514062
OpenAlexW2734885010

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.