Evidence map›Paper›PMID 28717205›Full record

ArticleScientific reports2017

Genome reconstruction in Cynara cardunculus taxa gains access to chromosome-scale DNA variation.

Alberto Acquadro, Lorenzo Barchi, Ezio Portis, Giulio Mangino, Danila Valentino, Giovanni Mauromicale, Sergio Lanteri

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Assessing Functional Conservation AmongstPlants (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Bioactive Compounds from Artichoke and Application Potential.Food technology and biotechnology · 2023
    Review
  6. Article
  7. Article
  8. Towards a Cardoon (International journal of molecular sciences · 2021
    Article
  9. Active Packaging-Releasing System withFoods (Basel, Switzerland) · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alberto AcquadroDISAFA, Plant Genetics and Breeding, University of Torino, Torino, Italy.ORCID 0000-0002-5322-9701
Lorenzo BarchiDISAFA, Plant Genetics and Breeding, University of Torino, Torino, Italy.ORCID 0000-0001-6414-4239
Ezio PortisDISAFA, Plant Genetics and Breeding, University of Torino, Torino, Italy. ezio.portis@unito.it.ORCID 0000-0002-1548-6096
Giulio ManginoDISAFA, Plant Genetics and Breeding, University of Torino, Torino, Italy.
Danila ValentinoDISAFA, Plant Genetics and Breeding, University of Torino, Torino, Italy.ORCID 0000-0002-9171-1232
Giovanni MauromicaleDi3A, Dipartimento di Agricoltura, Alimentazione e Ambiente, University of Catania, Catania, Italy.ORCID 0000-0003-0933-9302
Sergio LanteriDISAFA, Plant Genetics and Breeding, University of Torino, Torino, Italy.ORCID 0000-0003-3012-8710

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genome sequence of globe artichoke (Cynara cardunculus L. var. scolymus, 2n = 2x = 34) is now available for use. A survey of C. cardunculus genetic resources is essential for understanding the evolution of the species, carrying out genetic studies and for application of breeding strategies. We report on the resequencing analyses (~35×) of four globe artichoke genotypes, representative of the core varietal types, as well as a genotype of the related taxa cultivated cardoon. The genomes were reconstructed at a chromosomal scale and structurally/functionally annotated. Gene prediction indicated a similar number of genes, while distinctive variations in miRNAs and resistance gene analogues (RGAs) were detected. Overall, 23,5 M SNP/indel were discovered (range 6,34 M -14,50 M). The impact of some missense SNPs on the biological functions of genes involved in the biosynthesis of phenylpropanoid and sesquiterpene lactone secondary metabolites was predicted. The identified variants contribute to infer on globe artichoke domestication of the different varietal types, and represent key tools for dissecting the path from sequence variation to phenotype. The new genomic sequences are fully searchable through independent Jbrowse interfaces (www.artichokegenome.unito.it), which allow the analysis of collinearity and the discovery of genomic variants, thus representing a one-stop resource for C. cardunculus genomics.

Indexed as

Genome, PlantChromosome MappingCynaraEvolution, MolecularGenotypeINDEL MutationInternetMutation, MissensePlant BreedingPolymorphism, Single NucleotideSequence Analysis, DNA

Identifiers

PMID28717205
PMCPMC5514137

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.