ArticleScientific reports2017
Mother's Pre-pregnancy BMI and Placental Candidate miRNAs: Findings from the ENVIRONAGE Birth Cohort.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 24 citations in OpenAlex.
- Interpretable machine learning for predicting placental abruption in early-onset preeclampsia: model development and evaluation.Frontiers in medicine · 2025Article
- Up-regulated mRNA expression of VEGFA receptors (FLT1 and KDR) in placentas after assisted reproductive technology fertilization.Journal of applied genetics · 2024Article
- Article
- Maternal Body Mass Index Is Associated with Profile Variation in Circulating MicroRNAs at First Trimester of Pregnancy.Biomedicines · 2022Article
- Epigenetic Profiling in the Saliva of Obese Pregnant Women.Nutrients · 2022Observational
- Western diet-induced shifts in the maternal microbiome are associated with altered microRNA expression in baboon placenta and fetal liver.Frontiers in clinical diabetes and healthcare · 2022Article
- Significance of Sex Differences in ncRNAs Expression and Function in Pregnancy and Related Complications.Biomedicines · 2021Review
- Pre-pregnancy BMI-associated miRNA and mRNA expression signatures in the placenta highlight a sexually-dimorphic response to maternal underweight status.Scientific reports · 2021Article
- Maternal diabetes alters microRNA expression in fetal exosomes, human umbilical vein endothelial cells and placenta.Pediatric research · 2021Article
- Genome-wide microRNA expression analysis in human placenta reveals sex-specific patterns: an ENVIREpigenetics · 2021Article
- MicroRNA-mRNA Networks in Pregnancy Complications: A Comprehensive Downstream Analysis of Potential Biomarkers.International journal of molecular sciences · 2021Review
- Placental microRNAs: Responders to environmental chemicals and mediators of pathophysiology of the human placenta.Toxicology reports · 2020Review
- MicroRNA Profiling in HIV-Infected South African Women with Gestational Diabetes Mellitus.Molecular diagnosis & therapy · 2019Article
- Sex-specific associations between telomere length and candidate miRNA expression in placenta.Journal of translational medicine · 2018Article
- Decreased Expression of Circulating miR-20a-5p in South African Women with Gestational Diabetes Mellitus.Molecular diagnosis & therapy · 2018Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is increasing evidence that the predisposition for development of chronic diseases arises at the earliest times of life. In this context, maternal pre-pregnancy weight might modify fetal metabolism and the child's predisposition to develop disease later in life. The aim of this study is to investigate the association between maternal pre-pregnancy body mass index (BMI) and miRNA alterations in placental tissue at birth. In 211 mother-newborn pairs from the ENVIRONAGE birth cohort, we assessed placental expression of seven miRNAs important in crucial cellular processes implicated in adipogenesis and/or obesity. Multiple linear regression models were used to address the associations between pre-pregnancy BMI and placental candidate miRNA expression. Maternal pre-pregnancy BMI averaged (±SD) 23.9 (±4.1) kg/m
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