Evidence map›Paper›PMID 28717031›Full record

ArticleInfection and immunity2017

Phagocytic Receptors Activate Syk and Src Signaling during Borrelia burgdorferi Phagocytosis.

Tess L Killpack, Maria Ballesteros, Stephen C Bunnell, Alice Bedugnis, Lester Kobzik, Linden T Hu, Tanja Petnicki-Ocwieja

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Croquemort elicits activation of the immune deficiency pathway in ticks.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Article
  7. Article
  8. Immune Response toCurrent issues in molecular biology · 2021
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tess L KillpackDepartment of Biological Sciences, Wellesley College, Wellesley, Massachusetts, USA.
Maria BallesterosDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.
Stephen C BunnellDepartment of Integrative Physiology and Pathobiology, Tufts University School of Medicine, Boston, Massachusetts, USA.
Alice BedugnisDepartment of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA.
Lester KobzikDepartment of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA.
Linden T HuDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.
Tanja Petnicki-OcwiejaDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA tanja.petnicki_ocwieja@tufts.edu.
Tufts University · USWellesley College · US

Funding

Training in Education and Critical Research SkillsK12GM074869 · NIGMS · TUFTS UNIVERSITY BOSTON · PI MOORE, CLAIRE L · 2006 to 2017
$8.5M
Biochemical and Spatial Regulation of IKKg/NEMO During T Cell ActivationR01AI103022 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BUNNELL, STEPHEN C, KANE, LAWRENCE P. · 2013 to 2017
$3.0M
Mechanisms of Integrin-Mediated Costimulation in T CellsR01AI076575 · NIAID · TUFTS UNIVERSITY BOSTON · PI BUNNELL, STEPHEN C · 2009 to 2013
$1.9M
Role of innate immune tolerance in the pathogenesis of Lyme diseaseR21AI126757 · NIAID · TUFTS UNIVERSITY BOSTON · PI HU, LINDEN T · 2016 to 2017
$454k
Role of Endosomal Localization in Toll-like receptor 2 Responses to BorreliaR21AI097971 · NIAID · TUFTS MEDICAL CENTER · PI HU, LINDEN T · 2012 to 2013
$437k
Analysis of Tgsl, a novel regulator of macrophage survivalR21AI097855 · NIAID · TUFTS MEDICAL CENTER · PI BOYARTCHUK, VICTOR L · 2013 to 2014
$423k
NIAID NIH HHS R01 AI076575NIAID NIH HHS R01 AI103022NIAID NIH HHS R21 AI097855NIAID NIH HHS R21 AI097971NIAID NIH HHS R21 AI126757NIGMS NIH HHS K12 GM074869
6 · The paper itself

Abstract

Phagocytosis of the Lyme disease-causing pathogen

Indexed as

PhagocytosisSignal TransductionAnimalsBorrelia burgdorferiIntegrin beta ChainsLyme DiseaseMiceReceptors, ImmunologicReceptors, Scavengersrc-Family KinasesSyk KinaseIntegrin beta ChainsMarco protein, mouseReceptors, ImmunologicReceptors, Scavengersrc-Family KinasesSyk KinaseSyk protein, mouseBorrelia burgdorferiintegrin beta 1Lyme diseaseMARCOphagocytosisscavenger receptorSrc family kinaseSyk

Identifiers

PMID28717031
PMCPMC5607427
OpenAlexW2735059494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.