Evidence map›Paper›PMID 28717007›Full record

ArticleThe Journal of biological chemistry2017

Epigenetic suppression of human telomerase (

Dhurjhoti Saha, Ankita Singh, Tabish Hussain, Vivek Srivastava, Suman Sengupta, Anirban Kar, Parashar Dhapola, Vishnu Dhople, Ramesh Ummanni, Shantanu Chowdhury

Open access · hybridAbstract readComparative Study
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
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  3. Review
  4. Article
  5. Review
  6. Article
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  9. Article
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  12. Crosstalk between G-quadruplex and ROS.Cell death & disease · 2023
    Review
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  17. Article
  18. G-quadruplex DNA: a novel target for drug design.Cellular and molecular life sciences : CMLS · 2021
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Dhurjhoti SahaFrom the Genomics and Molecular Medicine Unit.
Ankita SinghFrom the Genomics and Molecular Medicine Unit.
Tabish HussainFrom the Genomics and Molecular Medicine Unit.
Vivek SrivastavaFrom the Genomics and Molecular Medicine Unit.
Suman SenguptaFrom the Genomics and Molecular Medicine Unit.
Anirban KarFrom the Genomics and Molecular Medicine Unit.
Parashar DhapolaG.N.R. Knowledge Centre for Genome Informatics, and.
Vishnu DhopleCentre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India.
Ramesh UmmanniCentre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India.
Shantanu ChowdhuryFrom the Genomics and Molecular Medicine Unit, shantanuc@igib.res.in.
Academy of Scientific and Innovative Research · INIndian Institute of Chemical Technology · INInstitute of Genomics and Integrative Biology · IN

Funding

DBT-Wellcome Trust India Alliance 500127-Z-09-ZWellcome Trust
6 · The paper itself

Abstract

Transcriptional activation of the human telomerase reverse transcriptase (

Indexed as

Epigenetic RepressionG-QuadruplexesPromoter Regions, GeneticAmino Acid SubstitutionCarcinomaCell Line, TumorCells, CulturedChromatin ImmunoprecipitationFibrosarcomaGenes, ReporterHistone DemethylasesHumansMutagenesis, Site-DirectedNeoplasm ProteinsNM23 Nucleoside Diphosphate KinasesPoint MutationHistone DemethylasesKDM1A protein, humanNeoplasm ProteinsNM23 Nucleoside Diphosphate KinasesNME1 protein, humanNME2 protein, humanRE1-Silencing Transcription FactorRecombinant ProteinsRepressor ProteinsTelomeraseTERT protein, humanchromatin modificationepigeneticsG-quadruplexNME2REST repressor complextelomerase reverse transcriptase (TERT)transcription regulation

Identifiers

PMID28717007
PMCPMC5602382
OpenAlexW2735481204

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.