Evidence map›Paper›PMID 28717004›Full record

ArticleThe Journal of biological chemistry2017

Two tyrosine residues, Tyr-108 and Tyr-503, are responsible for the deprotonation of phenolic substrates in vanillyl-alcohol oxidase.

Tom A Ewing, Quoc-Thai Nguyen, Robert C Allan, Gudrun Gygli, Elvira Romero, Claudia Binda, Marco W Fraaije, Andrea Mattevi, Willem J H van Berkel

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 31 citations in OpenAlex.

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  7. Retroconversion of estrogens into androgens by bacteria via a cobalamin-mediated methylation.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  8. The steroid side-chain-cleaving aldolase Ltp2-ChsH2The Journal of biological chemistry · 2019
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Tom A EwingFrom the Laboratory of Biochemistry, Wageningen University & Research, Stippeneng 4, 6708 WE Wageningen, The Netherlands.
Quoc-Thai Nguyenthe Department of Biology and Biotechnology, University of Pavia, Via Ferrata 9, 27100 Pavia, Italy.
Robert C AllanFrom the Laboratory of Biochemistry, Wageningen University & Research, Stippeneng 4, 6708 WE Wageningen, The Netherlands.
Gudrun GygliFrom the Laboratory of Biochemistry, Wageningen University & Research, Stippeneng 4, 6708 WE Wageningen, The Netherlands.
Elvira Romerothe Molecular Enzymology Group, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands, and.
Claudia Bindathe Department of Biology and Biotechnology, University of Pavia, Via Ferrata 9, 27100 Pavia, Italy.
Marco W Fraaijethe Molecular Enzymology Group, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands, and.
Andrea Mattevithe Department of Biology and Biotechnology, University of Pavia, Via Ferrata 9, 27100 Pavia, Italy.
Willem J H van BerkelFrom the Laboratory of Biochemistry, Wageningen University & Research, Stippeneng 4, 6708 WE Wageningen, The Netherlands, willem.vanberkel@wur.nl.
Wageningen University & Research · NLUniversity of Groningen · NLUniversity of Pavia · ITHo Chi Minh City Medicine and Pharmacy University · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A number of oxidoreductases from the VAO/

Indexed as

Models, MolecularAlcohol OxidoreductasesAllyl CompoundsAmino Acid SubstitutionBenzyl AlcoholsBinding, CompetitiveBiocatalysisCatalytic DomainCrystallography, X-RayEnzyme InhibitorsEnzyme StabilityEugenolFungal ProteinsMutagenesis, Site-DirectedOxidation-ReductionPenicillium4-allylphenolAlcohol OxidoreductasesAllyl CompoundsBenzyl AlcoholsEnzyme InhibitorsEugenolFungal ProteinsisoeugenolPhenolsTyrosinevanillyl alcoholvanillyl-alcohol oxidasecatalysisdeprotonationenzyme kineticsenzyme mechanismflavoproteintyrosine

Identifiers

PMID28717004
PMCPMC5582857
OpenAlexW2735042890

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.