Evidence map›Paper›PMID 28716823›Full record

ArticlePediatrics2017

Father Loss and Child Telomere Length.

Colter Mitchell, Sara McLanahan, Lisa Schneper, Irv Garfinkel, Jeanne Brooks-Gunn, Daniel Notterman

Open access · bronzeAbstract read
In one paragraph

Article in Pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 65 citations in OpenAlex.

  1. Epigenetic regulation of brain development, plasticity, and response to early-life stress.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Childhood Adversity and Telomere Length.Biological research for nursing · 2025
    Article
  6. Article
  7. Article
  8. Paternal Incarceration, Race and Ethnicity, and Maternal Health.Journal of racial and ethnic health disparities · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Colter MitchellUniversity of Michigan, Ann Arbor, Michigan.
Sara McLanahanPrinceton University, Princeton, New Jersey; and.
Lisa SchneperPrinceton University, Princeton, New Jersey; and.
Irv GarfinkelColumbia University, New York, New York.
Jeanne Brooks-GunnColumbia University, New York, New York.
Daniel NottermanPrinceton University, Princeton, New Jersey; and dan1@princeton.edu.
Princeton University · USColumbia University · USUniversity of Michigan–Ann Arbor · US

Funding

Fragile Families and the Transition to AdulthoodR01HD036916 · NICHD · PRINCETON UNIVERSITY · PI Kathryn Edin, Jane Waldfogel · 1999 to 2026
$46.3M
Reciprocal Genetic-Environmental Interactions During Childhood and AdolescenceR01HD076592 · NICHD · PRINCETON UNIVERSITY · PI NOTTERMAN, DANIEL A. · 2013 to 2023
$6.8M
ECONOMIC STATUS, PUBLIC POLICY, AND CHILD NEGLECTR01HD039135 · NICHD · PRINCETON UNIVERSITY · PI PAXSON, CHRISTINA H · 2000 to 2004
$3.1M
Child Care and Parental Employment in Fragile FamiliesR01HD040421 · NICHD · COLUMBIA UNIVERSITY TEACHERS COLLEGE · PI BROOKS-GUNN, JEANNE · 2002 to 2006
$2.8M
Scientific and Technical Computing CoreP2CHD047879 · NICHD · PRINCETON UNIVERSITY · PI SALGANIK, MATTHEW J. · 2014 to 2018
$2.0M
Future of Families and Child Wellbeing Study Summer Data WorkshopR25HD074544 · NICHD · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Amanda Geller, Julien O Teitler · 2013 to 2026
$1.5M
NICHD NIH HHS P2C HD047879NICHD NIH HHS R01 HD036916NICHD NIH HHS R01 HD039135NICHD NIH HHS R01 HD040421NICHD NIH HHS R01 HD076592NICHD NIH HHS R25 HD074544
6 · The paper itself

Abstract

BACKGROUND AND

objectivesFather loss during childhood has negative health and behavioral consequences, but the biological consequences are unknown. Our goal was to examine how father loss (because of separation and/or divorce, death, or incarceration) is associated with cellular function as estimated by telomere length.

methodsData come from the 9-year follow-up of the Fragile Families and Child Wellbeing Study, a birth cohort study of children in 20 large American cities (

resultsAt 9 years of age, children with father loss have significantly shorter telomeres (14% reduction). Paternal death has the largest association (16%), followed by incarceration (10%), and separation and/or divorce (6%). Changes in income partially mediate these associations (95% mediation for separation and/or divorce, 30% for incarceration, and 25% for death). Effects are 40% greater for boys and 90% greater for children with the most reactive alleles of the serotonin transporter genes when compared with those with the least reactive alleles. No differences were found by age at father loss or a child's race/ethnicity.

conclusionsFather loss has a significant association with children's sTL, with the death of a father showing the largest effect. Income loss explains most of the association between child sTL and separation and/or divorce but much less of the association with incarceration or death. This underscores the important role of fathers in the care and development of children and supplements evidence of the strong negative effects of parental incarceration.

Indexed as

Paternal DeprivationAdolescentAge FactorsAllelesCase-Control StudiesChildChild, PreschoolCohort StudiesDopamine Plasma Membrane Transport ProteinsFemaleFollow-Up StudiesHumansIncomeInfantInfant, NewbornMaleDopamine Plasma Membrane Transport ProteinsSerotonin Plasma Membrane Transport Proteins

Identifiers

PMID28716823
PMCPMC5527665
OpenAlexW2739320527

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.