Observational studyBMJ open2017
Human papillomavirus prevalence and genotype distribution among young women and men in Maputo city, Mozambique.
Observational study in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Global and regional estimates of genital human papillomavirus prevalence among men: a systematic review and meta-analysis.The Lancet. Global health · 2023Pooled it
- Prevalence and Genotype Distribution of High-Risk Human Papillomavirus Infection Among Sub-Saharan African Women: A Systematic Review and Meta-Analysis.Frontiers in public health · 2022Pooled it
- Trial
- Implementing voluntary counselling and testing services among university students in Mozambique: a mixed methods process evaluation.Frontiers in public health · 2026Article
- Article
- Evaluation of hpv risk groups among women enrolled in the mulher cervical cancer screening study in Mozambique.Infectious agents and cancer · 2025Article
- Endocervical adenocarcinomas and HPV genotyping in an HIV endemic milieu - a retrospective study.BMC women's health · 2025Article
- Oncogenic human papillomavirus infection (HPV 16/18) and associated factors among women in East Gojjam Zone, NorthWest Ethiopia 2021.African health sciences · 2024Article
- PD-L1 expression in squamous cervical carcinomas of Mozambican women living with or without HIV.Scientific reports · 2024Article
- Article
- Article
- Article
- Differential etiopathogenic features of vulvar squamous cell carcinomas in sub-Saharan Africa and Europe.International journal of cancer · 2023Article
- Genotype heterogeneity of high-risk human papillomavirus infection in Ethiopia.Frontiers in microbiology · 2023Article
- Human papillomavirus prevalence in male and female university students in Gaborone, Botswana.Epidemiology and infection · 2022Article
- Cervical human papillomavirus genotypes in a high HIV setting: A scoping review of a decade of human papillomavirus epidemiological research in Botswana.Frontiers in medicine · 2022Article
- Role of Immunity and Vaginal Microbiome in Clearance and Persistence of Human Papillomavirus Infection.Frontiers in cellular and infection microbiology · 2022Review
- Article
- Viral load and high prevalence of HR-HPV52 and 58 types in black women from rural communities.BMC infectious diseases · 2021Article
- Frequent high-risk HPV co-infections excluding types 16 or 18 in cervical neoplasia in Guadeloupe.BMC cancer · 2021Observational
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesHuman papillomavirus (HPV) is a well-known cause of cervical cancer, the second most frequent cancer in female African populations. This study aimed at determining the prevalence of HPV infections and the genotype distribution in young adults aged 18-24, in Maputo city, Mozambique, and to assess the suitability of commercially available HPV vaccines.
methodsThis cross-sectional study was conducted between 2009 and 2011 at a youth clinic in Maputo Central Hospital. Cervical and urethral samples were obtained from 236 women and 176 men, respectively. Demographic and behavioural data were collected using structured questionnaires. HPV genotyping was performed for 35 different high, probably or possibly high-risk and low-risk HPV types using the CLART Human Papillomavirus 2.
resultsHPV prevalence was 168/412 (40.8%; 95% CI 36.0 to 45.5) and was significantly higher in women than in men (63.6%vs10.2%). HPV52 was the most frequent type found in women, followed by HPV35, -16,-53, -58,-6 and -51. In men, HPV51 ranked the highest, followed by HPV6, -11,-52, -59 and -70. HIV infection and sexual debut before 18 years of age were associated with multiple HPV infections (OR 3.03; 95% CI 1.49 to 6.25 and OR 6.03; 95% CI 1.73 to 21.02, respectively). Women had a significantly higher HPV infection prevalence than men (p<0.001). The 9-valent HPV vaccine would cover 36.8% of the high-risk genotypes circulating in women in this study, compared with 26.3% and 15.8% coverage by the bivalent and quadrivalent vaccines, respectively.
conclusionThis study confirmed the high burden of HPV infections in young women in Maputo city, Mozambique. The HPV prevalence was associated with high-risk sexual behaviour. Sex education and sexually transmitted infection prevention interventions should be intensified in Mozambique. Only a proportion of the high-risk HPV genotypes (37%) were covered by currently available vaccines.
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