Evidence map›Paper›PMID 28716326›Full record

ReviewThe Urologic clinics of North America2017

Disease-Specific Outcomes of Botulinum Toxin Injections for Neurogenic Detrusor Overactivity.

Aaron Kaviani, Rose Khavari

Abstract readReview
In one paragraph

Review in The Urologic clinics of North America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Botulinum Toxin Use in Neurourology.Reviews in urology · 2018
    Article
  10. Botulinum Neurotoxin, an Example of Successful Translational Research.Clinical pharmacology and translational medicine · 2018
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Aaron KavianiDepartment of Urology, Houston Methodist Hospital, 6560 Fannin Street, Suite 2100, Houston, TX 77030, USA.
Rose KhavariDepartment of Urology, Houston Methodist Hospital, 6560 Fannin Street, Suite 2100, Houston, TX 77030, USA. Electronic address: rkhavari@houstonmethodist.org.

Funding

Multidisciplinary K12 Urologic Research (KURe) Career Development ProgramK12DK083014 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI LAMB, DOLORES JEAN · 2008 to 2017
$6.0M
NIDDK NIH HHS K12 DK083014
6 · The paper itself

Abstract

Intradetrusor injection of botulinum toxin A (BTX-A) is an effective option for managing patients with neurogenic detrusor overactivity (NDO) who do not respond to or tolerate oral pharmacologic agents. There is level I evidence that intradetrusor injection of onabotulinumtoxinA for refractory NDO in patients with multiple sclerosis and spinal cord injury is associated with a significantly greater achievement of goals and improved performance in urodynamic studies than placebo. Pilot studies or small case series support BTX-A for NDO in patients with Parkinson's disease and cerebrovascular accident. BTX-A seems to be effective in children with myelomeningocele. However, no adult data exists.

Indexed as

Administration, IntravesicalBotulinum Toxins, Type AClinical Trials as TopicHumansNeuromuscular AgentsTreatment OutcomeUrinary Bladder, OveractiveBotulinum Toxins, Type ANeuromuscular AgentsBotulinum toxinDetrusor overactivityMultiple sclerosisMyelomeningoceleNeurogenicOveractive bladderParkinson’s diseaseUrinary incontinence

Identifiers

PMID28716326
PMCPMC5604875

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.