ReviewExpert reviews in molecular medicine2017
Bilateral Wilms tumour: a review of clinical and molecular features.
Review in Expert reviews in molecular medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 2 syntheses or guidelines pooled it, 123 citations in OpenAlex.
- Wilms Tumor Management: A Systematic Review Comparing SIOP and NWTS/COG Protocols in Diagnosis, Treatment, and Outcome.Asian Pacific journal of cancer prevention : APJCP · 2025Pooled it
- The UMBRELLA SIOP-RTSG 2016 Wilms tumour pathology and molecular biology protocol.Nature reviews. Urology · 2018Guideline
- Long-term outcomes and patterns of relapse in patients with bilateral Wilms tumor or bilaterally predisposed unilateral Wilms tumor, a report from the COG AREN0534 study.International journal of cancer · 2024Trial
- Characteristics and outcome of synchronous bilateral Wilms tumour in the SIOP WT 2001 Study: Report from the SIOP Renal Tumour Study Group (SIOP-RTSG).British journal of cancer · 2024Trial
- Bilateral Wilms Tumor: Looking for the Best Surgical Strategy.Annals of surgical oncology · 2026Article
- DLX6-AS1 promotes the progression of Wilms tumor by sponging miR-195-5p to upregulate KIF23 in Wilms tumor cells.Discover oncology · 2026Article
- Case Report: Bilateral Wilms tumor with TP53 mutation: a case-based review of clinical challenges.Frontiers in surgery · 2026Article
- Tracing metastatic spread in pediatric solid tumors using copy number and targeted deep sequencing.The Journal of pathology · 2025Article
- Wilms tumor characteristics in children with heterozygous germline DIS3L2 variants.Genetics in medicine : official journal of the American College of Medical Genetics · 2025Article
- A rare case of fetal bilateral Wilms' tumor in horseshoe kidney: A case report.International journal of surgery case reports · 2025Article
- Paediatric renal tumors: An insight into molecular characteristics, histomorphology and syndromic association.World journal of nephrology · 2025Review
- Wilms' Tumor: A Review of Clinical Characteristics, Treatment Advances, and Research Opportunities.Medicina (Kaunas, Lithuania) · 2025Review
- A review of the genetic background in complicated WT1-related disorders.Clinical and experimental nephrology · 2025Review
- Clinical outcome of 115 patients with synchronous bilateral Wilms' tumor: largest cohort of single-center experience.Frontiers in oncology · 2025Article
- Acute pyelonephritis and subcapsular hematoma revealing a nephroblastoma.Radiology case reports · 2025Article
- A novel nephrometry scoring system outperforms RENAL score, PADUA score, and SPARE score for feasibility prediction of nephron-sparing surgery in children with bilateral Wilms tumor.Quantitative imaging in medicine and surgery · 2024Article
- Pursuit of the optimal therapeutic approach and intensity for children with bilateral Wilms tumour.British journal of cancer · 2024Article
- Inter-Ethnic Variations in the Clinical, Pathological, and Molecular Characteristics of Wilms Tumor.Cancers · 2024Review
- Response of bilateral Wilms tumor to chemotherapy suggests histologic subtype and guides treatment.Journal of the National Cancer Institute · 2024Article
- Insights into Personalized Care Strategies for Wilms Tumor: A Narrative Literature Review.Biomedicines · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
Wilms tumour (WT) is the most common paediatric kidney cancer and affects approximately one in 10 000 children. The tumour is associated with undifferentiated embryonic lesions called nephrogenic rests (NRs) or, when diffuse, nephroblastomatosis. WT or NRs can occur in both kidneys, termed bilateral disease, found in only 5-8% of cases. Management of bilateral WT presents a major clinical challenge in terms of maximising survival, preserving renal function and understanding underlying genetic risk. In this review, we compile clinical data from 545 published cases of bilateral WT and discuss recent progress in understanding the molecular basis of bilateral WT and its associated precursor NRs in the context of the latest radiological, surgical and epidemiological features.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.