Evidence map›Paper›PMID 28716157›Full record

ReviewParasitology2018

Advances and challenges in barcoding pathogenic and environmental Leptospira.

Vanina Guernier, Kathryn J Allan, Cyrille Goarant

Open access · greenAbstract readReview
In one paragraph

Review in Parasitology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 4 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 4 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Isolation and Culture of Leptospira from Clinical and Environmental Samples.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  7. Leptospirosis.Nature reviews. Disease primers · 2025
    Review
  8. Article
  9. How Is Bovine Genital Leptospirosis Diagnosed Under Field Conditions?Animals : an open access journal from MDPI · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Global distribution ofmedRxiv : the preprint server for health sciences · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Application of Multilocus Sequence Typing for the Characterization ofTropical medicine and infectious disease · 2023
    Article
  18. Article
  19. Article
  20. Regional Prevalence of IntermediatePathogens (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Vanina GuernierAustralian Institute of Tropical Health and Medicine,James Cook University,1 James Cook Drive,Townsville,QLD 4811,Australia.
Kathryn J AllanInstitute of Biodiversity Animal Health and Comparative Medicine,College of Medical Veterinary and Life Sciences,University of Glasgow,University Avenue,Glasgow, G12 8QQ,UK.
Cyrille GoarantInstitut Pasteur in New Caledonia,Institut Pasteur International Network,Leptospirosis Research and Expertise Unit,Noumea,New Caledonia. 11 rue Paul Doumer,BP 61;98845 Noumea cedex,New Caledonia.ORCID 0000-0002-0690-9464
Australian Institute of Tropical Health and Medicine · AUUniversity of Glasgow · GBUniversity of New Caledonia · NC

Funding

Wellcome Trust 096400
6 · The paper itself

Abstract

Leptospirosis is a zoonotic bacterial disease of global importance. A large spectrum of asymptomatic animal hosts can carry the infection and contribute to the burden of human disease. Environmental sources of human contamination also point to the importance of a hydrotelluric reservoir. Leptospirosis can be caused by as many as 15 different pathogenic or intermediate Leptospira species. However, classification of these bacteria remains complicated through the use of both serological and genetic classification systems that show poor correlation. With the advent of molecular techniques, DNA-based barcoding offers a conceptual framework that can be used for leptospirosis surveillance as well as source tracking. In this review, we summarize some of the current techniques, highlight significant successes and weaknesses and point to the future opportunities and challenges to successfully establish a widely applicable barcoding scheme for Leptospira.

Indexed as

Environmental MicrobiologyAnimalsDisease ReservoirsDNA Barcoding, TaxonomicGenotyping TechniquesHumansLeptospiraLeptospirosisPhylogenyZoonosesbarcodingepidemiologygenotypingLeptospirazoonotic reservoir

Identifiers

PMID28716157
PMCPMC6010154
OpenAlexW2734512401

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.